CRISPR

CRISPR4-ikzf1

ID

ZDB-CRISPR-230725-6

Name

CRISPR4-ikzf1

Previous Names

None

Target

Sequence

5' - GGACATGCCTGCATCTGAGA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
fr105	ikzf1

Expression

Gene expression in Wild Types + CRISPR4-ikzf1

No data available

Phenotype

Phenotype resulting from CRISPR4-ikzf1

No data available

Phenotype of all Fish created by or utilizing CRISPR4-ikzf1

Phenotype	Fish	Conditions	Figures
T cell differentiation disrupted, abnormal	ikzf1^fr105/fr105	standard conditions	Figure 1 from Hess et al., 2022
whole organism rag1 expression decreased amount, abnormal	ikzf1^fr105/fr105	standard conditions	Figure 1 from Hess et al., 2022
lymphoid progenitor cell differentiation disrupted, abnormal	ikzf1^fr105/fr105	standard conditions	Figure 1 from Hess et al., 2022
erythrocyte differentiation increased process quality, abnormal	ikzf1^fr105/fr105	standard conditions	Figure 1 from Hess et al., 2022
whole organism ikzf1 expression increased amount, abnormal	ikzf1^fr105/fr105	standard conditions	Figure 1 from Hess et al., 2022
myeloid cell differentiation increased process quality, abnormal	ikzf1^fr105/fr105	standard conditions	Figure 1 from Hess et al., 2022
T cell differentiation disrupted, abnormal	ikzf1^fr105/fr105; fr101Tg	standard conditions	Figure 1 from Hess et al., 2022
thymus EGFP expression absent, abnormal	ikzf1^fr105/fr105; fr101Tg	standard conditions	Figure 1 from Hess et al., 2022

Citations