CRISPR

CRISPR1-pcsk9

ID
ZDB-CRISPR-230518-1
Name
CRISPR1-pcsk9
Previous Names
None
Target
Sequence
5' - GCATCCCATGGAACCTGCAG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
The PAM site was "CGG" at the 3' end.
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
tpu7 pcsk9
tpu8 pcsk9
Expression
Gene expression in Wild Types + CRISPR1-pcsk9
No data available
Phenotype
Phenotype resulting from CRISPR1-pcsk9
No data available
Phenotype of all Fish created by or utilizing CRISPR1-pcsk9
Phenotype Fish Conditions Figures
liver socs3a expression decreased amount, abnormal pcsk9tpu7/tpu7 (AB) bacterial treatment by injection: Streptococcus pneumoniae TIGR4 Fig. 3 with image from Jacome Sanz et al., 2021
whole organism semi-viable, abnormal pcsk9tpu7/tpu7 (AB) bacterial treatment by injection: Streptococcus pneumoniae TIGR4 Fig. 2 with image from Jacome Sanz et al., 2021
brain pcsk9 expression decreased amount, abnormal pcsk9tpu7/tpu7 (AB) standard conditions Fig. 1 with image from Jacome Sanz et al., 2021
whole organism viability, abnormal pcsk9tpu7/tpu7 (AB) bacterial treatment by injection: Streptococcus pneumoniae TIGR4 Fig. 2 with image from Jacome Sanz et al., 2021
liver hamp expression decreased amount, abnormal pcsk9tpu7/tpu7 (AB) bacterial treatment by injection: Streptococcus pneumoniae TIGR4 Fig. 3 with image from Jacome Sanz et al., 2021
liver ldlrap1a expression increased amount, abnormal pcsk9tpu7/tpu7 (AB) bacterial treatment by injection: Streptococcus pneumoniae TIGR4 Fig. 3 with image from Jacome Sanz et al., 2021
whole organism viability, abnormal pcsk9tpu8/tpu8 (AB) bacterial treatment by injection: Streptococcus pneumoniae TIGR4 Fig. 2 with image from Jacome Sanz et al., 2021
whole organism semi-viable, abnormal pcsk9tpu8/tpu8 (AB) bacterial treatment by injection: Streptococcus pneumoniae TIGR4 Fig. 2 with image from Jacome Sanz et al., 2021
brain pcsk9 expression decreased amount, abnormal pcsk9tpu8/tpu8 (AB) standard conditions Fig. 1 with image from Jacome Sanz et al., 2021
whole organism semi-viable, abnormal pcsk9tpu7/+ (AB) bacterial treatment by injection: Streptococcus pneumoniae TIGR4 Fig. 2 with image from Jacome Sanz et al., 2021
whole organism viability, abnormal pcsk9tpu7/+ (AB) bacterial treatment by injection: Streptococcus pneumoniae TIGR4 Fig. 2 with image from Jacome Sanz et al., 2021
whole organism semi-viable, abnormal pcsk9tpu8/+ (AB) bacterial treatment by injection: Streptococcus pneumoniae TIGR4 Fig. 2 with image from Jacome Sanz et al., 2021
whole organism viability, abnormal pcsk9tpu8/+ (AB) bacterial treatment by injection: Streptococcus pneumoniae TIGR4 Fig. 2 with image from Jacome Sanz et al., 2021
Citations
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