CRISPR

CRISPR1-psen2

ID

ZDB-CRISPR-190304-7

Name

CRISPR1-psen2

Previous Names

None

Target

psen2 (1)

Sequence

5' - GAATTCGGTGCTCAACACTC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ia52	psen2
uaa7	psen2
uaa8	psen2

Expression

Gene expression in Wild Types + CRISPR1-psen2

No data available

Phenotype

Phenotype resulting from CRISPR1-psen2

No data available

Phenotype of all Fish created by or utilizing CRISPR1-psen2

Phenotype	Fish	Conditions	Figures
whole organism Ab9-map1lc3b labeling increased amount, abnormal	psen2^ia52/ia52	food availability	Figure 6 from Barazzuol et al., 2023
startle response increased process quality, abnormal	psen2^ia52/ia52	control	Figure 3 from Barazzuol et al., 2023
brain Ab9-map1lc3b labeling increased amount, abnormal	psen2^ia52/ia52	standard conditions	Figure 6 from Barazzuol et al., 2023
integument decreased pigmentation, abnormal	psen2^ia52/ia52	standard conditions	Figure 1 from Barazzuol et al., 2023
brain psen2 expression decreased amount, abnormal	psen2^ia52/ia52	standard conditions	Figure 1 from Barazzuol et al., 2023
whole organism autophagy increased process quality, abnormal	psen2^ia52/ia52	control	Figure 6 from Barazzuol et al., 2023
whole organism Ab9-map1lc3b labeling increased amount, abnormal	psen2^ia52/ia52	control	Figure 6 from Barazzuol et al., 2023
whole organism Ab9-map1lc3b labeling increased amount, abnormal	psen2^ia52/ia52	chemical treatment by environment: bafilomycin A1, food availability	Figure 6 from Barazzuol et al., 2023
melanophore stripe melanin biosynthetic process decreased process quality, abnormal	psen2^ia52/ia52	standard conditions	Figure 1 from Barazzuol et al., 2023
whole organism Ab9-map1lc3b labeling increased amount, abnormal	psen2^ia52/ia52	chemical treatment by environment: sirolimus, chemical treatment by environment: bafilomycin A1	Figure 6 from Barazzuol et al., 2023
brain autophagy increased process quality, abnormal	psen2^ia52/ia52	standard conditions	Figure 6 from Barazzuol et al., 2023
whole organism Ab9-map1lc3b labeling increased amount, abnormal	psen2^ia52/ia52	chemical treatment by environment: bafilomycin A1	Figure 6 from Barazzuol et al., 2023
melanophore stripe melanocyte decreased pigmentation, abnormal	psen2^uaa7/uaa7	standard conditions	Fig 1 from Jiang et al., 2020 Fig. 5 from Jiang et al., 2018
melanophore stripe melanocyte decreased pigmentation, abnormal	psen2^uaa8/uaa8	standard conditions	Fig. 5 from Jiang et al., 2018

Citations