CRISPR

CRISPR1-traf4a

ID
ZDB-CRISPR-181115-1
Name
CRISPR1-traf4a
Previous Names
None
Target
Sequence
5' - AGCGTCTCTTGGGCTTCTCC - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
ca301 traf4a
Expression
Gene expression in Wild Types + CRISPR1-traf4a
No data available
Phenotype
Phenotype resulting from CRISPR1-traf4a
No data available
Phenotype of all Fish created by or utilizing CRISPR1-traf4a
Phenotype Fish Conditions Figures
optic vesicle decreased size, abnormal traf4aca301/ca301 standard conditions Fig. 5 with image from Hehr et al., 2018
optic vesicle increased variability of size, abnormal traf4aca301/ca301 standard conditions Fig. 5 with image from Hehr et al., 2018
head bilateral symmetry, abnormal traf4aca301/ca301 standard conditions Fig. 5 with image from Hehr et al., 2018
head bilateral symmetry, abnormal traf4aca301/ca301 + MO1-traf4a standard conditions Fig. 6 with image from Hehr et al., 2018
optic vesicle decreased size, abnormal traf4aca301/ca301 + MO1-traf4a standard conditions Fig. 6 with image from Hehr et al., 2018
optic vesicle increased variability of size, abnormal traf4aca301/ca301 + MO1-traf4a standard conditions Fig. 6 with image from Hehr et al., 2018
eye apoptotic process increased occurrence, abnormal traf4aca301/ca301 + MO1-traf4a standard conditions Fig. 6 with image from Hehr et al., 2018
optic vesicle decreased size, abnormal traf4aca301/ca301; zf460Tg standard conditions Fig. 6 with image from Hehr et al., 2018
optic vesicle epithelium disorganized, abnormal traf4aca301/ca301; zf460Tg standard conditions Fig. 6 with image from Hehr et al., 2018
optic vesicle increased variability of size, abnormal traf4aca301/ca301; zf460Tg standard conditions Fig. 6 with image from Hehr et al., 2018
optic vesicle apical surface ab1-prkcz labeling spatial pattern, abnormal traf4aca301/ca301; zf460Tg standard conditions Fig. 7 with image from Hehr et al., 2018
epithelium adherens junction organization disrupted, abnormal traf4aca301/ca301; zf460Tg standard conditions Fig. 6 with imageFig. 7 with image from Hehr et al., 2018
optic vesicle ab1-prkcz labeling mislocalised, abnormal traf4aca301/ca301; zf460Tg standard conditions Fig. 7 with image from Hehr et al., 2018
optic cup morphogenesis involved in camera-type eye development disrupted, abnormal traf4aca301/ca301; zf460Tg standard conditions Fig. 8 with image from Hehr et al., 2018
optic vesicle asymmetrical, abnormal traf4aca301/ca301; zf460Tg standard conditions Fig. 6 with image from Hehr et al., 2018
optic vesicle neuroepithelial cell displaced to posterior segment eye anatomical space, abnormal traf4aca301/ca301; zf460Tg standard conditions Fig. 6 with image from Hehr et al., 2018
optic vesicle establishment of apical/basal cell polarity disrupted, abnormal traf4aca301/ca301; zf460Tg standard conditions Fig. 7 with image from Hehr et al., 2018
optic vesicle elongation disrupted, abnormal traf4aca301/ca301; zf460Tg standard conditions Fig. 8 with image from Hehr et al., 2018
optic vesicle ab1-lama1 labeling mislocalised, abnormal traf4aca301/ca301; zf460Tg standard conditions Fig. 7 with image from Hehr et al., 2018
optic vesicle apical surface ab1-tjp1 labeling spatial pattern, abnormal traf4aca301/ca301; zf460Tg standard conditions Fig. 7 with image from Hehr et al., 2018
optic vesicle basal surface ab1-lama1 labeling spatial pattern, abnormal traf4aca301/ca301; zf460Tg standard conditions Fig. 7 with image from Hehr et al., 2018
Citations