CRISPR

CRISPR1-stxbp1b

ID

ZDB-CRISPR-160505-2

Name

CRISPR1-stxbp1b

Previous Names

None

Target

stxbp1b (1)

Sequence

5' - GGCGAGAGCGAGCACTC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
s3001	stxbp1b

Expression

Gene expression in Wild Types + CRISPR1-stxbp1b

No data available

Phenotype

Phenotype resulting from CRISPR1-stxbp1b

No data available

Phenotype of all Fish created by or utilizing CRISPR1-stxbp1b

Phenotype	Fish	Conditions	Figures
transmission of nerve impulse disrupted, abnormal	stxbp1b^s3001/s3001	standard conditions	Fig. 1 from Moog et al., 2022
optic tectum action potential, abnormal	stxbp1b^s3001/s3001	standard conditions	Fig. 1 from Moog et al., 2022
transmission of nerve impulse process quality, ameliorated	stxbp1b^s3001/s3001	chemical treatment by environment: trazodone	Fig. 3 from Moog et al., 2022
optic tectum action potential, ameliorated	stxbp1b^s3001/s3001	chemical treatment by environment: trazodone	Fig. 3 from Moog et al., 2022
transmission of nerve impulse process quality, ameliorated	stxbp1b^s3001/s3001	chemical treatment by environment: clemizole	Fig. 3 from Moog et al., 2022
optic tectum action potential, ameliorated	stxbp1b^s3001/s3001	chemical treatment by environment: clemizole	Fig. 3 from Moog et al., 2022
whole organism decreased mobility, abnormal	stxbp1b^s3001/s3001 (WIK)	light duration	Fig. 6 from Grone et al., 2016
forebrain electric potential, abnormal	stxbp1b^s3001/s3001 (WIK)	standard conditions	Fig. 10 from Grone et al., 2016
whole organism increased pigmentation, abnormal	stxbp1b^s3001/s3001 (WIK)	standard conditions	Fig. 4 from Grone et al., 2016
whole organism immobile, abnormal	stxbp1b^s3001/s3001 (WIK)	light duration	Fig. 5 from Grone et al., 2016
locomotory behavior process quality, abnormal	stxbp1b^s3001/s3001 (WIK)	light duration	Fig. 5, Fig. 6 from Grone et al., 2016
optic tectum calcium-mediated signaling duration, ameliorated	mitfa^w2/w2; stxbp1b^s3001/s3001	chemical treatment by environment: heptan-1-ol	Figure 6 from Liu et al., 2021
midbrain neuronal action potential increased occurrence, abnormal	mitfa^w2/w2; stxbp1b^s3001/s3001	standard conditions	Figure 1 from Liu et al., 2021
optic tectum calcium-mediated signaling increased duration, abnormal	mitfa^w2/w2; stxbp1b^s3001/s3001	standard conditions	Figure 3 from Liu et al., 2021
optic tectum calcium-mediated signaling spatial distribution of a process, ameliorated	mitfa^w2/w2; stxbp1b^s3001/s3001	chemical treatment by environment: propofol	Figure 6 from Liu et al., 2021
skeletal muscle contraction increased frequency, abnormal	mitfa^w2/w2; stxbp1b^s3001/s3001	standard conditions	Figure 1 from Liu et al., 2021
optic tectum calcium-mediated signaling increased frequency, abnormal	mitfa^w2/w2; stxbp1b^s3001/s3001	standard conditions	Figure 7 from Liu et al., 2021
optic tectum calcium-mediated signaling frequency, ameliorated	mitfa^w2/w2; stxbp1b^s3001/s3001	chemical treatment by environment: propofol	Figure 6 from Liu et al., 2021
optic tectum calcium-mediated signaling increased spatial extent of a process, abnormal	mitfa^w2/w2; stxbp1b^s3001/s3001	standard conditions	Figure 2 , Figure 3 , Figure 7 from Liu et al., 2021
optic tectum calcium-mediated signaling duration, ameliorated	mitfa^w2/w2; stxbp1b^s3001/s3001	chemical treatment by environment: propofol	Figure 6 from Liu et al., 2021
optic tectum calcium-mediated signaling spatial distribution of a process, ameliorated	mitfa^w2/w2; stxbp1b^s3001/s3001	chemical treatment by environment: heptan-1-ol	Figure 6 from Liu et al., 2021
optic tectum calcium-mediated signaling frequency, ameliorated	mitfa^w2/w2; stxbp1b^s3001/s3001	chemical treatment by environment: heptan-1-ol	Figure 6 from Liu et al., 2021
locomotory behavior process quality, abnormal	stxbp1a^s3000/+; stxbp1b^s3001/+	standard conditions	Fig. 7 from Grone et al., 2016
whole organism decreased mobility, abnormal	stxbp1a^s3000/+; stxbp1b^s3001/+	standard conditions	Fig. 7 from Grone et al., 2016

Citations