CRISPR

CRISPR2-dhx15

ID

ZDB-CRISPR-160128-279

Name

CRISPR2-dhx15

Previous Names

Target

Sequence

5' - GGATGTCATGCTGGGTCAGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
hg93	dhx15

Expression

Gene expression in Wild Types + CRISPR2-dhx15

No data available

Phenotype

Phenotype resulting from CRISPR2-dhx15

No data available

Phenotype of all Fish created by or utilizing CRISPR2-dhx15

Phenotype	Fish	Conditions	Figures
whole organism dead, abnormal	dhx15^hg93/hg93	standard conditions	Fig. S3 from McElderry et al., 2019
whole organism tp53 expression increased amount, abnormal	dhx15^hg93/hg93	standard conditions	Fig. 5 from McElderry et al., 2019
post-vent region increased curvature, abnormal	dhx15^hg93/hg93	standard conditions	Fig. S3 from McElderry et al., 2019
pectoral fin deformed, abnormal	dhx15^hg93/hg93	standard conditions	Fig. S3 from McElderry et al., 2019
whole organism ab11-tp53 labeling increased amount, abnormal	dhx15^hg93/hg93	standard conditions	Fig. 5 from McElderry et al., 2019
whole organism mdm2 expression increased amount, abnormal	dhx15^hg93/hg93	standard conditions	Fig. 5, Fig. S9 from McElderry et al., 2019
mRNA splicing, via spliceosome process quality, abnormal	dhx15^hg93/hg93	standard conditions	Fig. 5 from McElderry et al., 2019
alternative mRNA splicing, via spliceosome increased process quality, abnormal	dhx15^hg93/hg93	standard conditions	Fig. 5 from McElderry et al., 2019
head decreased size, abnormal	dhx15^hg93/hg93	standard conditions	Fig. S3 from McElderry et al., 2019
pericardium edematous, abnormal	dhx15^hg93/hg93	standard conditions	Fig. S3 from McElderry et al., 2019
whole organism mdm2 expression increased amount, abnormal	dhx15^hg93/hg93; tp53^hg91/hg91	standard conditions	Fig. S9 from McElderry et al., 2019

Citations