Expression patterns of the thioredoxin reductase (A–H), glutathione/thioredoxin reductase (I–P) and 15 kDa selenoprotein (Q–R) during development in zebrafish embryos. Development stage is indicated in the right lower corner (G, gastrula; 5s, 5 somites; 16s, 16 somites or in hours post-fertilization). AD, adaxial cells; AF, axial fin fold; BL, blood; CNS, central nervous system; I, intestine; IB, intestinal bulb; L, liver; LL, lateral line; MY, myotomes; N, notochord; OT, otic vesicle; P, polster; PF, pectoral fins; PP, prechordal plate; PT, posterior tectum; R, retina; S, somites; SC, spinal chord; TE, tectum; VHM, ventral hematopoetic mesoderm.

Expression patterns of the glutathione peroxidase (A–F) and phospholipid hyperoxide glutathione peroxidases (G–L) during development in zebrafish embryos. Development stage is indicated in the right lower corner in hours (h) or days (d) post-fertilization. AV, axial vasculature; E, eye; EP, epiphysis; HE, head; I, intestine; IB, intestinal bulb; L, liver; LL, lateral line; MPD, medial part of the pronephric duct; MY, myotomes; PLG, posterior lateral line ganglion; PR, photoreceptor cell layer of the retina; PT, posterior tectum; R, retina; SB, swim bladder; TE, tectum; YSL, yolk syncytial layer.

Expression patterns of the selenoprotein Pa (A–C), selenoprotein Pb (D–F) and methionine R-sulfoxide reductase (G–I) during development in zebrafish embryos. Development stage is indicated in the right lower corner (G, gastrula; 14s, 14 somites or in hours (h) or days (d) post-fertilization). BVZ, brain ventricular zone; H, heart; HM, head mesenchyme; I, intestine; IB, intestinal bulb; K, kidney; L, liver; LP, liver primordium; OT, otic vesicle; P, polster; PD, pronephric duct; PM, paraxial mesoderm; TE, tectum; VM, ventral mesenchyme; YSL, yolk syncytial layer.

Expression patterns of the iodothyronine deiodinase type 1 (A–D) and type 2 (E–L) during development in zebrafish embryos. Development stage is indicated in the right lower corner in hours (h) or days (d) post-fertilization. AH, adenohypophysis; I, intestine; IB, intestinal bulb; K, kidney; L, liver; R, retina; SB, swim bladder.

Expression patterns of the selenoprotein N (A–H) and selenoprotein M (I–P) during development in zebrafish embryos. Development stage is indicated in the right lower corner (G, gastrula; 5s, 5 somites; 16s, 16 somites or in hours post-fertilization). AF, axial fin fold; AM, axial mesoderm; AS, anterior somites; DNS, dorsal spinal chord neurons; HE, head; IR, intermediate cell layer of the retina; LL, lateral line; M, margin; N, notochord; P, polster; PF, pectoral fins; PS, posterior somites; S, somites; TB, tail bud; TE, tectum; VME, ventral mesoderm.

Expression patterns of the different forms of selenoprotein W (A–F) and selenoprotein T (G–I). The zebrafish embryos were examined at 24 (H lower panel), 48 h (A, C, E, G, H upper panel, I) or 5 days post-fertilization (B, D, F). BA, branchial arches; BL, blood; IR, intermediate cell layer of the retina; L, liver; LL, lateral line; NO, nose; OT, otic vesicle; OV, olfactory vesicle; PO, proctodeum; PR, photoreceptor cell layer of the retina; SB, swim bladder.

Expression patterns of selenoproteins SePH (A–C) and selenophosphate synthetase SPS2 (D–F) in zebrafish embryos. The development stage is indicated in the right corner of each panel in hours post-fertilization. BVZ, brain ventricular zone; IB, intestinal bulb; K, kidney; L, liver; MY, myotomes; OV, olfactory vesicle; PD, pronephric duct; PF, pectoral fins; PT, posterior tectum; PZR, proliferative zone of the retina; R, retina; TE, tectum.