Phenotype: | cGAS/STING signaling pathway increased process quality, ameliorated |
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Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
Name: | cGAS/STING signaling pathway |
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Synonyms: | |
Definition: | The series of molecular signals initiated by the binding of a double-stranded DNA or RNA from another organism to cytosolic cyclic GMP-AMP (cGAMP) synthase (cGAS) that activates innate immune responses through production of the second messenger cGAMP, which activates the adaptor STING. |
Ontology: | GO: Biological Process [GO:0140896] QuickGO AmiGO |
Name: | increased process quality |
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Synonyms: | |
Definition: | A quality of a process that has a value that is increased compared to normal or average. |
Ontology: | Phenotypic Quality Ontology [PATO:0002304] |
Tag: | ameliorated |
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Definition: | This annotation denotes a significantly rescued phenotype resulting from an additional reagent or mutation. |