cGAS/STING signaling pathway

Term ID

GO:0140896

Synonyms

Definition

The series of molecular signals initiated by the binding of a double-stranded DNA or RNA from another organism to cytosolic cyclic GMP-AMP (cGAMP) synthase (cGAS) that activates innate immune responses through production of the second messenger cGAMP, which activates the adaptor STING. (3)

References

Ontology

GO: Biological Process    QuickGO    AmiGO