Phenotype: | G2/M transition of mitotic cell cycle delayed, abnormal |
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Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
Name: | G2/M transition of mitotic cell cycle |
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Synonyms: | mitotic G2/M transition |
Definition: | The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex. |
Ontology: | GO: Biological Process [GO:0000086] QuickGO AmiGO |
Name: | delayed |
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Synonyms: | late |
Definition: | A quality of a process which starts later than the natural start time or the reference process. |
Ontology: | Phenotypic Quality Ontology [PATO:0000502] |