Search Ontology:
GO: Biological Process

G2/M transition of mitotic cell cycle

Term ID
GO:0000086
Synonyms
  • mitotic G2/M transition
Definition
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
References
  • Reactome:R-HSA-69275
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is part of
is a type of
negatively regulated by
positively regulated by
regulated by
Phenotype
Phenotype caused by Genes