Search Ontology:
GO: Biological Process
G2/M transition of mitotic cell cycle
- Term ID
- GO:0000086
- Synonyms
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- mitotic G2/M transition
- Definition
- The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
- References
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- Reactome:R-HSA-69275
- Ontology
- GO: Biological Process QuickGO AmiGO
- is part of
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- is a type of
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- negatively regulated by
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- positively regulated by
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- regulated by
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Phenotype
Phenotype caused by Genes