execution phase of necroptosis

Term ID

GO:0097528

Synonyms

• execution phase of necroptotic process
• necroptosis
• necroptotic execution phase

Definition

A stage of the necroptotic process that starts after a necroptotic signal has been relayed to the execution machinery. Key steps of the execution phase are swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. The execution phase ends when the cell has died. 20823910

References

Ontology

GO: Biological Process    QuickGO    AmiGO