MyD88-dependent toll-like receptor signaling pathway

Term ID

GO:0002755

Synonyms

MyD88-dependent TLR signaling pathway
MyD88-dependent toll-like receptor signalling pathway

Definition

A toll-like receptor signaling pathway in which the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response. (6)

References

Reactome:R-HSA-166058
Reactome:R-HSA-975871

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is a type of: toll-like receptor signaling pathway

toll-like receptor signaling pathway Show first 5 Terms
has subtype: MyD88-dependent toll-like receptor 2 signaling pathway MyD88-dependent toll-like receptor 4 signaling pathway

MyD88-dependent toll-like receptor 2 signaling pathway MyD88-dependent toll-like receptor 4 signaling pathway Show first 5 Terms
negatively regulated by: negative regulation of MyD88-dependent toll-like receptor signaling pathway

negative regulation of MyD88-dependent toll-like receptor signaling pathway Show first 5 Terms
positively regulated by: positive regulation of MyD88-dependent toll-like receptor signaling pathway

positive regulation of MyD88-dependent toll-like receptor signaling pathway Show first 5 Terms
regulated by: regulation of MyD88-dependent toll-like receptor signaling pathway

regulation of MyD88-dependent toll-like receptor signaling pathway Show first 5 Terms

Phenotype

Phenotype caused by Genes