toll-like receptor signaling pathway

Term ID

GO:0002224

Synonyms

TLR signaling pathway
toll-like receptor signalling pathway

Definition

The series of molecular signals initiated by a ligand binding to a toll-like receptor of a target cell. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response. (6)

References

Reactome:R-HSA-168898

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is a type of: pattern recognition receptor signaling pathway

pattern recognition receptor signaling pathway Show first 5 Terms
has subtype: MyD88-dependent toll-like receptor signaling pathway MyD88-independent toll-like receptor signaling pathway TIRAP-dependent toll-like receptor signaling pathway toll-like receptor 21 signaling pathway toll-like receptor TLR1:TLR2 signaling pathway ... Show All 6 Terms

MyD88-dependent toll-like receptor signaling pathway MyD88-independent toll-like receptor signaling pathway TIRAP-dependent toll-like receptor signaling pathway toll-like receptor 21 signaling pathway toll-like receptor TLR1:TLR2 signaling pathway toll-like receptor TLR6:TLR2 signaling pathway Show first 5 Terms
negatively regulated by: negative regulation of toll-like receptor signaling pathway

negative regulation of toll-like receptor signaling pathway Show first 5 Terms
positively regulated by: positive regulation of toll-like receptor signaling pathway

positive regulation of toll-like receptor signaling pathway Show first 5 Terms
regulated by: regulation of toll-like receptor signaling pathway

regulation of toll-like receptor signaling pathway Show first 5 Terms

Phenotype

Phenotype caused by Genes