Search Ontology:
ChEBI
mycophenolate mofetil
- Term ID
- CHEBI:8764
- Synonyms
-
- 2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate
- 2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
- Cellcept
- MMF
- mycophenolic acid morpholinoethyl ester
- RS 61443
- Definition
- A carboxylic ester resulting from the formal condensation between the carboxylic acid group of mycophenolic acid and the hydroxy group of 2-(morpholin-4-yl)ethanol. In the liver, it is metabolised to mycophenolic acid, an immunosuppressant for which it is a prodrug. It is widely used to prevent tissue rejection following organ transplants as well as for the treatment of certain autoimmune diseases.
- References
-
- CAS:128794-94-5
- DrugBank:DB00688
- Drug_Central:1859
- HMDB:HMDB0014826
- KEGG:C07908
- KEGG:D00752
- PMID:11099793
- PMID:11490743
- PMID:15572389
- PMID:15992049
- PMID:16979992
- PMID:19858585
- PMID:21180633
- PMID:21710356
- PMID:22081165
- PMID:22294686
- PMID:22310598
- PMID:22417996
- PMID:22460418
- PMID:22560143
- PMID:8826401
- PMID:9274835
- Reaxys:7500599
- Wikipedia:Mycophenolate_mofetil
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_functional_parent
-
- has_role
-
Phenotype
Phenotype resulting from mycophenolate mofetil
Phenotype where environments contain mycophenolate mofetil
Phenotype modified by environments containing mycophenolate mofetil
Human Disease / Model Data