Search Ontology:
ChEBI
trametinib
- Term ID
- CHEBI:75998
- Synonyms
-
- GSK 1120212
- JTP 74057
- N-(3-{3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl}phenyl)acetamide
- trametinib
- trametinibum
- Definition
- A pyridopyrimidine that is used (as its dimethyl sulfoxide addition compound) for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment.
- References
-
- CAS:871700-17-3
- Chemspider:9881833
- DrugBank:DB08911
- Drug_Central:4802
- KEGG:D10175
- LINCS:LSM-1143
- PMCID:PMC7715110
- PMID:21523318
- PMID:22245957
- PMID:23035153
- PMID:23237773
- PMID:23248257
- PMID:23290787
- PMID:23432625
- PMID:23438367
- PMID:23441129
- PMID:23533766
- PMID:23583440
- PMID:23587417
- PMID:23649971
- PMID:23658559
- PMID:23709751
- PMID:23807941
- PMID:23844038
- PMID:23846731
- PMID:23893461
- PMID:23971497
- PMID:23977666
- PMID:24055054
- PMID:26119340
- PMID:33922284
- PMID:34034619
- PMID:34145930
- PMID:34156985
- PMID:34282746
- PMID:34355652
- PMID:34413035
- PMID:34421360
- PMID:34484797
- PMID:34516041
- PMID:34590600
- PMID:34592184
- Patent:WO2005121142
- Patent:WO2011038082
- Patent:WO2011038085
- Patent:WO2011047238
- Reaxys:12497153
- Wikipedia:Trametinib
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
- inverse has_part
-
Phenotype
Phenotype resulting from trametinib
Phenotype where environments contain trametinib
Phenotype modified by environments containing trametinib
Human Disease Model