Search Ontology:
ChEBI
trametinib dimethyl sulfoxide
- Term ID
- CHEBI:75991
- Synonyms
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- GSK1120212
- GSK1120212B
- JTP 74057
- Mekinist
- N-(3-{3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl}phenyl)acetamide--(methylsulfinyl)methane (1/1)
- Trametinib DMSO
- Definition
- An addition compound obtained by combining equimolar amounts of trametinib and dimethyl sulfoxide. Used for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment.
- References
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- CAS:1187431-43-1
- DrugBank:DB08911
- KEGG:D10176
- PMID:21245089
- PMID:22169769
- PMID:22389471
- PMID:22507781
- PMID:23248257
- PMID:23432625
- PMID:23848983
- PMID:24025354
- PMID:24030134
- Patent:WO2005121142
- Reaxys:12497280
- Wikipedia:Trametinib
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_part
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- has_role
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Phenotype
Phenotype resulting from trametinib dimethyl sulfoxide
Phenotype where environments contain trametinib dimethyl sulfoxide
Phenotype modified by environments containing trametinib dimethyl sulfoxide
Human Disease Model