PD173074

Term ID

CHEBI:63448

Synonyms

1-tert-butyl-3-[2-{[4-(diethylamino)butyl]amino}-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea
PD 173074
PD-173074

Definition

A member of the class of ureas that is 1-tert-butylurea in which one of the hydrogens attached to N(3) is substituted by a pyrido[2,3-d]pyrimidin-7-yl group, which is itself substituted at positions 2 and 6 by a 4-(diethylamino)butyl]amino group and a 3,5-dimethoxyphenyl group, respectively. It is a FGF/VEGF receptor tyrosine kinase inhibitor.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic amine biaryl dimethoxybenzene pyridopyrimidine tertiary amino compound ... Show All 6 Terms

aromatic amine biaryl dimethoxybenzene pyridopyrimidine tertiary amino compound ureas Show first 5 Terms
has_functional_parent: PD-166866

PD-166866 Show first 5 Terms
has_role: antineoplastic agent EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor fibroblast growth factor receptor antagonist

antineoplastic agent EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor fibroblast growth factor receptor antagonist Show first 5 Terms

Phenotype

Phenotype resulting from PD173074

Phenotype where environments contain PD173074

Phenotype modified by environments containing PD173074

Human Disease Model