Search Ontology:
ChEBI
entecavir hydrate
- Term ID
- CHEBI:59902
- Synonyms
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- 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1,9-dihydro-6H-purin-6-one--water (1/1)
- 9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)guanine monohydrate
- entecavir
- entecavir monohydrate
- Definition
- The monohydrate form of entecavir. A synthetic analogue of 2'-deoxyguanosine, entecavir is a nucleoside reverse transcriptase inhibitor with selective antiviral activity against hepatitis B virus. It is phosphorylated intracellularly to the active triphosphate form, which competes with deoxyguanosine triphosphate, the natural substrate of hepatitis B virus reverse transcriptase, inhibiting every stage of the enzyme's activity, although it has no activity against HIV. Enteclavir is used for the treatment of chronic hepatitis B.
- References
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- CAS:209216-23-9
- DrugBank:DB00442
- KEGG:D04008
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_part
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- has_role
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Phenotype
Phenotype resulting from entecavir hydrate
Phenotype where environments contain entecavir hydrate
Phenotype modified by environments containing entecavir hydrate
Human Disease / Model Data