Search Ontology:
ChEBI
dutasteride
- Term ID
- CHEBI:521033
- Synonyms
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- (5alpha,17beta)-N-(2,5-bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
- alpha,alpha,alpha,alpha',alpha',alpha'-hexafluoro-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxy-2',5'-xylidide
- N-[2,5-bis(trifluoromethyl)phenyl]-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide
- Definition
- An aza-steroid that is inasteride in which the tert-butyl group is replaced by a 2,5-bis(trifluoromethyl)phenyl group. A synthetic 4-azasteroid, dutasteride is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5alpha-reductase, an intracellular enzyme that converts testosterone to 5alpha-dihydrotestosterone. Dutasteride is used for the treatment of symptomatic benign prostatic hyperplasia in men with an enlarged prostate gland.
- References
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- Beilstein:7401530
- CAS:164656-23-9
- DrugBank:DB01126
- Drug_Central:973
- KEGG:D03820
- Patent:WO9507927
- Wikipedia:Dutasteride
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_parent_hydride
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- has_role
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Phenotype
Phenotype resulting from dutasteride
Phenotype where environments contain dutasteride
Phenotype modified by environments containing dutasteride
Human Disease / Model Data