EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor

Term ID

CHEBI:50781

Synonyms

3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) (EC 1.3.1.22) inhibitor
3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) (EC 1.3.1.22) inhibitors
3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) inhibitor
3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) inhibitors
3-oxo-5alpha-steroid 4-dehydrogenase inhibitor
3-oxo-5alpha-steroid 4-dehydrogenase inhibitors
3-oxo-5alpha-steroid:NADP+ Delta(4)-oxidoreductase inhibitor
3-oxo-5alpha-steroid:NADP+ Delta(4)-oxidoreductase inhibitors
3-oxosteroid 5alpha-reductase inhibitor
3-oxosteroid Delta4-dehydrogenase inhibitor
4-ene-3-oxosteroid 5alpha-reductase inhibitor
4-ene-5alpha-reductase inhibitor
5alpha-oxidoreductase inhibitor
5alpha-oxidoreductase inhibitors
5alpha-reductase inhibitor
5alpha-reductase inhibitors
cholest-4-en-3-one 5alpha-reductase inhibitor
cholestenone 5alpha-reductase inhibitor
cholestenone 5alpha-reductase inhibitors
Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitor
Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitors
EC 1.3.1.22 (3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))) inhibitor
EC 1.3.1.22 (3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))) inhibitors
EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitors
EC 1.3.1.22 inhibitor
EC 1.3.1.22 inhibitors
reduced nicotinamide adenine dinucleotide phosphate:Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitor
reduced nicotinamide adenine dinucleotide phosphate:Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitors
steroid 5alpha-hydrogenase inhibitor
steroid 5alpha-hydrogenase inhibitors
steroid 5alpha-reductase inhibitor
steroid 5alpha-reductase inhibitors
testosterone 5alpha-reductase inhibitor
testosterone 5alpha-reductase inhibitors
testosterone Delta(4)-5alpha-reductase inhibitor
testosterone Delta(4)-5alpha-reductase inhibitors
testosterone Delta(4)-hydrogenase inhibitor
testosterone Delta(4)-hydrogenase inhibitors

Definition

An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of of 3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)), EC 1.3.1.22, the enzyme which converts testosterone (CHEBI:17347) into the more potent androgen 5alpha-dihydrotestosterone.

References

Wikipedia:5-alpha-reductase_inhibitor

Ontology

ChEBI ( EBI )

Relationships

is a type of: EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor

EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor Show first 5 Terms
inverse has_role: 3',4',5-trihydroxy-3,7-dimethoxyflavone 3',4',7-trihydroxyisoflavone 4-pregnen-20,21-diol-3-one dutasteride finasteride ... Show All 7 Terms

3',4',5-trihydroxy-3,7-dimethoxyflavone 3',4',7-trihydroxyisoflavone 4-pregnen-20,21-diol-3-one dutasteride finasteride impatienol prunetin Show first 5 Terms

Phenotype

Phenotype resulting from EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor

Phenotype where environments contain EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor

Phenotype modified by environments containing EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor

Human Disease / Model Data