EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor

Term ID

CHEBI:50750

Synonyms

• DNA gyrase inhibitor
• DNA gyrase inhibitors
• DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitor
• DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitors
• DNA topoisomerase (ATP-hydrolysing) inhibitor
• DNA topoisomerase (ATP-hydrolysing) inhibitors
• DNA topoisomerase II inhibitor
• DNA topoisomerase II inhibitors
• EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitor
• EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitors
• EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitors
• EC 5.99.1.3 inhibitor
• EC 5.99.1.3 inhibitors
• inhibitor of type II topoisomerase
• inhibitors of type II topoisomerase
• topoisomerase II inhibitor
• topoisomerase II inhibitors
• topoisomerase-II inhibitor
• topoisomerase-II inhibitors
• type II DNA topoisomerase inhibitor
• type II DNA topoisomerase inhibitors

Definition

A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.

References

Ontology

ChEBI  ( EBI )