Term: | Muller cell G1/S transition of mitotic cell cycle |
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Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
Name: | Muller cell |
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Synonyms: | Mueller cell, Muller cells |
Definition: | Glial cell of the retina that forms a support structure stretching radially across the thickness of the retina. Muller cell bodies are found in the inner nuclear layer and send projection to the outer limiting membrane and inner limiting membrane. |
Ontology: | Anatomy Ontology [ZFA:0009280] |
Name: | G1/S transition of mitotic cell cycle |
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Synonyms: | |
Definition: | The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated. |
Ontology: | GO: Biological Process [GO:0000082] QuickGO AmiGO |