G1/S transition of mitotic cell cycle

Term ID

GO:0000082

Synonyms

Definition

The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.

References

Reactome:R-HSA-69206

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is part of: mitotic cell cycle

mitotic cell cycle Show first 5 Terms
is a type of: cell cycle G1/S phase transition mitotic cell cycle phase transition

cell cycle G1/S phase transition mitotic cell cycle phase transition Show first 5 Terms
negatively regulated by: negative regulation of G1/S transition of mitotic cell cycle

negative regulation of G1/S transition of mitotic cell cycle Show first 5 Terms
positively regulated by: positive regulation of G1/S transition of mitotic cell cycle

positive regulation of G1/S transition of mitotic cell cycle Show first 5 Terms
regulated by: regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle Show first 5 Terms

Phenotype

Phenotype caused by Genes