| Term: | liver low-density lipoprotein |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | liver |
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| Synonyms: | |
| Definition: | Solid compound organ with three lobes that has many functions including bile production, blood detoxification, the production of critical plasma proteins and clotting factors, complement proteins and the storage of many substances, such as lipids, amino acids, iron, and glycogen. Female fish produce vitellogenins in the liver. |
| Ontology: | Anatomy Ontology [ZFA:0000123] |
| Name: | low-density lipoprotein |
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| Synonyms: | beta-lipoproteins, LDL, low-density lipoproteins |
| Definition: | A class of lipoproteins of small size (18-25 nm) and low density (1.019-1.063 g/ml) particles with a core composed mainly of cholesterol esters and smaller amounts of triglycerides. The surface monolayer consists mostly of phospholipids, a single copy of apolipoprotein B-100, and free cholesterol molecules. The main function of LDL is to transport cholesterol and cholesterol esters from the liver. Excessive levels are associated with cardiovascular disease. |
| Ontology: | ChEBI [CHEBI:39026] ( EBI ) |