low-density lipoprotein

Term ID

CHEBI:39026

Synonyms

beta-lipoproteins
LDL
low-density lipoproteins

Definition

A class of lipoproteins of small size (18-25 nm) and low density (1.019-1.063 g/ml) particles with a core composed mainly of cholesterol esters and smaller amounts of triglycerides. The surface monolayer consists mostly of phospholipids, a single copy of apolipoprotein B-100, and free cholesterol molecules. The main function of LDL is to transport cholesterol and cholesterol esters from the liver. Excessive levels are associated with cardiovascular disease.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: lipoprotein

lipoprotein Show first 5 Terms
has subtype: electronegative low-density lipoprotein oxidised LDL

electronegative low-density lipoprotein oxidised LDL Show first 5 Terms
has_part: low-density lipoprotein cholesterol

low-density lipoprotein cholesterol Show first 5 Terms

Phenotype

Phenotype resulting from low-density lipoprotein

Phenotype where environments contain low-density lipoprotein

Phenotype modified by environments containing low-density lipoprotein

Human Disease Model