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Phenotype Figure Summary
Marker:
bmp6
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Styrkarsdottir
et al.
, 2023
Fig. 2
bmp6
z52/+
(TU)
centrum eroding, abnormal
centrum structure, abnormal
hemal arch morphology, abnormal
neural arch morphology, abnormal
vertebra cartilage tissue mislocalised, abnormal
Fig. S3
TU + CRISPR5-bmp6 + CRISPR6-bmp6
centrum bone tissue mislocalised, abnormal
centrum eroding, abnormal
centrum structure, abnormal
neural arch morphology, abnormal
Xu
et al.
, 2022
Fig. 2
bmp6
hj1/hj1
, 
bmp6
hj2/hj2
intermuscular bone absent, abnormal
intermuscular bone dorsal region absent, abnormal
Fig. 5
bmp6
hj1/hj1
, 
bmp6
hj2/hj2
BMP signaling pathway decreased process quality, abnormal
canonical NF-kappaB signal transduction increased process quality, abnormal
regulation of bone development decreased process quality, abnormal
regulation of osteoclast differentiation decreased process quality, abnormal
regulation of tumor necrosis factor production increased process quality, abnormal
Fig. 6
bmp6
hj2/hj2
; cy25Tg/cy25Tg
myoseptum osteoblast
acp5b
expression decreased amount, abnormal
myoseptum osteoblast GFP expression decreased amount, abnormal
myoseptum osteoclast
acp5b
expression increased amount, abnormal
myoseptum osteoclast GFP expression increased amount, abnormal
Fig. 7
bmp6
hj1/hj1
, 
bmp6
hj2/hj2
regulation of bone development increased process quality, abnormal
regulation of tumor necrosis factor production increased process quality, abnormal
whole organism
sik1
expression increased amount, abnormal
Fig. 8
bmp6
hj2/hj2
whole organism
sik1
expression increased amount, abnormal
Fig. 9
bmp6
hj2/hj2
regulation of osteoblast differentiation decreased process quality, abnormal
whole organism
alpl
expression decreased amount, abnormal
whole organism
dlx5a
expression decreased amount, abnormal
whole organism
runx2a
expression decreased amount, abnormal
whole organism
sp7
expression decreased amount, abnormal
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