Gene
bmp6
- ID
- ZDB-GENE-050306-42
- Name
- bone morphogenetic protein 6
- Symbol
- bmp6 Nomenclature History
- Previous Names
-
- zgc:113595
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable cytokine activity. Acts upstream of or within bone morphogenesis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including choroidal fissure; ectoderm; fin; intermuscular bone; and ventral mesoderm. Orthologous to human BMP6 (bone morphogenetic protein 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7139175 (27 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
{Iron overload, susceptibility to} | 620121 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR017948 | Transforming growth factor beta, conserved site |
Domain | IPR001111 | TGF-beta, propeptide |
Domain | IPR001839 | Transforming growth factor-beta, C-terminal |
Family | IPR015615 | Transforming growth factor-beta-related |
Homologous_superfamily | IPR029034 | Cystine-knot cytokine |
Domain Details Per Protein
Protein | Length | Cystine-knot cytokine | TGF-beta, propeptide | Transforming growth factor beta, conserved site | Transforming growth factor-beta, C-terminal | Transforming growth factor-beta-related |
---|---|---|---|---|---|---|
UniProtKB:A0A8M9PFZ4
|
406 | |||||
UniProtKB:Q5CZV5
|
417 |
Interactions and Pathways
Plasmids
No data available