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Phenotype Figure Summary
Marker:
apol1
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Kotb
et al.
, 2016
Fig. 3
AB + MO3-apol1
heart edematous, abnormal
pronephric capsular space increased size, abnormal
pronephric glomerular capillary collapsed, abnormal
pronephric glomerulus morphogenesis decreased process quality, abnormal
Fig. 4
li4Tg + MO3-apol1
, 
li4Tg + MO4-apol1
, 
li4Tg + MO1-apol1
pronephric capsular space increased size, abnormal
pronephric glomerular capillary collapsed, abnormal
pronephric glomerulus morphogenesis decreased process quality, abnormal
Fig. 5
lri500Tg + MO3-apol1
blood vasculature blood plasma EGFP expression decreased amount, abnormal
glomerular filtration decreased occurrence, abnormal
Fig. 6
li4Tg + MO3-apol1
, 
li4Tg + MO1-apol1
pronephric glomerulus morphogenesis decreased process quality, abnormal
pronephric podocyte
nphs1
expression decreased amount, abnormal
pronephric podocyte podocyte foot malformed, abnormal
whole organism
nphs1
expression decreased amount, abnormal
Anderson
et al.
, 2015
Fig. 2
AB/EKW + MO2-apol1
glomerular basement membrane podocyte foot morphology, abnormal
glomerular filtration disrupted, abnormal
pericardium edematous, abnormal
renal glomerulus microvillus protruding into renal capsular space, abnormal
slit diaphragm assembly disrupted, abnormal
yolk syncytial layer edematous, abnormal
Fig. 3
AB/EKW + CRISPR1-apol1
glomerular basement membrane podocyte foot morphology, abnormal
Fig. 5
AB/EKW + MO2-apol1
glomerular filtration disrupted, abnormal
whole organism edematous, abnormal
Fig. S4
AB/EKW + CRISPR1-apol1
, 
AB/EKW + MO2-apol1
glomerular basement membrane podocyte foot morphology, abnormal
podocyte disorganized, abnormal
Kotb
et al.
, 2014
Fig. 5
WT + MO1-apol1
glomerular filtration process quality, abnormal
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