Research
Search
Genes / Clones
Expression
Mutants / Tg
Antibodies
Anatomy / GO / Human Disease / Chemical
Publications
Data Mining
Downloads
Data Model
AllianceMine
BioMart
Genomics
BLAST
ZFIN
Ensembl
NCBI
UCSC
Genome Browsers
ZFIN
Ensembl
Vega
GRC
UCSC
NCBI
Resources
Zebrafish Genomics
Other Genome Databases
Resources
General
The Zebrafish Book
Protocol Wiki
Antibody Wiki
Anatomy Atlases
Resources for Students and Educators
Zebrafish Programs
ZF-Health
Husbandry Resources
More...
Resource Centers
Zebrafish International Resource Center (ZIRC)
China Zebrafish Resource Center (CZRC)
European Zebrafish Resource Center (EZRC)
Community
Announcements
News
Meetings
Jobs
Alliance Community Forum
Search
People
Labs
Companies
Societies
International Zebrafish Society (IZFS)
Zebrafish Disease Models Society (ZDMS)
Genetics Society of America (GSA)
Zebrafish Husbandry Association
Support
Nomenclature
Nomenclature Conventions
Line Designations
Wild-Type Lines
Submit a Proposed Gene Name
Submit a Proposed Mutant/Tg Line Name
Publications
Guidelines for Authors
Zebrashare
Citing ZFIN
Using ZFIN
Help & Tips
Glossary
Single Box Search Help
Submit Data
Terms of Use
About Us
About ZFIN
Contact Information
Statistics
Committees
Jobs at ZFIN
Sign In
Phenotype Figure Summary
Marker:
exosc8
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Müller
et al.
, 2020
Fig. 2
exosc8
cu201/cu201
whole organism
cbln8
expression decreased amount, abnormal
whole organism
otx2b
expression decreased amount, abnormal
whole organism
tp53
expression increased amount, abnormal
Figure 1.
exosc8
cu201/cu201
eye decreased size, abnormal
head decreased size, abnormal
swim bladder uninflated, abnormal
Figure 3.
exosc8
cu201/cu201
cerebellum decreased size, abnormal
midbrain decreased size, abnormal
Figure 4.
exosc8
cu201/cu201
head apoptotic process increased occurrence, abnormal
Figure 7.
exosc8
cu201/cu201
ceratohyal bone decreased length, abnormal
ceratohyal bone position, abnormal
Figure S3.
exosc8
cu201/cu201
motor neuron axon decreased branchiness, abnormal
Figure S4.
exosc8
cu201/cu201
caudal fin decreased thickness, abnormal
skeletal muscle cell disorganized, abnormal
Giunta
et al.
, 2016
Fig. 4
rw0Tg + MO2-exosc8
hindbrain morphogenesis disrupted, abnormal
hindbrain morphology, abnormal
Fig. 5
rw0Tg + MO2-exosc8
axonogenesis disrupted, abnormal
cerebellar Purkinje cell layer structural organization disrupted, abnormal
cerebellum Purkinje cell distributed, abnormal
cerebellum structure, abnormal
motor neuron axon branchiness, abnormal
motor neuron axon truncated, abnormal
Boczonadi
et al.
, 2014
Fig. 6
rw0Tg + MO1-exosc8
brain development disrupted, abnormal
eye decreased size, abnormal
eye shape, abnormal
pericardium edematous, abnormal
post-vent region decreased length, abnormal
whole organism malformed, abnormal
Fig. 7
WT + MO1-exosc8
lateral line nerve myelin sheath absent, abnormal
myelination of lateral line nerve axons disrupted, abnormal
Fig. 8
rw0Tg + MO1-exosc8 + MO4-tp53
brain development disrupted, abnormal
hindbrain morphology, abnormal
midbrain morphology, abnormal
text only
rw0Tg + MO1-exosc8
, 
rw0Tg + MO2-exosc8
brain development disrupted, abnormal
eye decreased size, abnormal
eye shape, abnormal
pericardium edematous, abnormal
post-vent region decreased length, abnormal
sensory perception of touch disrupted, abnormal
swimming disrupted, abnormal
whole organism malformed, abnormal
Phenotype Annotation (1994-2006)
Fig. for (hi1011)
exosc8
hi1011Tg
eye decreased size, abnormal
gut quality, abnormal
heart quality, abnormal
Fig. for (hi3709)
exosc8
hi3709Tg
eye decreased size, abnormal
gut quality, abnormal
heart quality, abnormal
Amsterdam
et al.
, 2004
text only
exosc8
hi1011Tg/hi1011Tg
eye decreased size, abnormal
gut hypoplastic, abnormal
head decreased size, abnormal
pericardium edematous, abnormal
Your Input Welcome
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Name:
Institution:
Email address:
Please leave blank:
Subject:
Comments:
Send your comments
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.