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Phenotype Figure Summary
Marker:
mcm5
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Wu
et al.
, 2021
Fig. 1
mcm5
zf3604/zf3604
(AB)
, 
AB + MO1-mcm5
eye decreased size, abnormal
fourth ventricle decreased size, abnormal
head decreased size, abnormal
hindbrain cranial motor neuron decreased amount, abnormal
midbrain hindbrain boundary blurry, abnormal
rhombomere 5 cranial motor neuron increased amount, abnormal
rhombomere 6 cranial motor neuron increased amount, abnormal
rhombomere 7 cranial motor neuron absence of anatomical entity, abnormal
rhombomere 7 cranial motor neuron decreased amount, abnormal
Fig. 2
mcm5
zf3604/zf3604
(AB)
, 
AB + MO1-mcm5
hindbrain Ab60-h3 labeling decreased distribution, abnormal
hindbrain cell population proliferation decreased process quality, abnormal
Fig. 3
AB + MO1-mcm5
hindbrain apoptotic process increased process quality, abnormal
Fig. 4
AB + MO1-mcm5
hindbrain
etv4
expression decreased distribution, abnormal
hindbrain
fgf8b
expression increased distribution, abnormal
hindbrain
fgfr1a
expression decreased distribution, abnormal
rhombomere 7 cranial motor neuron decreased amount, abnormal
Bicknell
et al.
, 2011
Fig. 5
AB + MO1-mcm5
embryo development disrupted, abnormal
whole organism anatomical surface decreased area, abnormal
whole organism dwarf-like, abnormal
Liu
et al.
, 2009
Fig. 1
AB + MO1-mcm5
gastrulation with mouth forming second disrupted, abnormal
regulation of mitotic cell cycle, embryonic disrupted, abnormal
Fig. 3
AB + MO1-mcm5
apoptotic process increased occurrence, abnormal
hypoblast apoptotic, abnormal
Phenotype Annotation (1994-2006)
Fig. for (m850)
mcm5
m850/m850
eye decreased size, abnormal
pharyngeal arch 3-7 skeleton quality, abnormal
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