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Phenotype Figure Summary
Marker:
id2a
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Xu
et al.
, 2016
Fig. S13
WT + MO1-id2a
liver
hhex
expression decreased amount, abnormal
Khaliq
et al.
, 2015
Fig. 3
gz15Tg; um14Tg + MO1-id2a
, 
WT + MO1-id2a
, 
jh1Tg; um14Tg + MO1-id2a
intestinal bulb decreased size, abnormal
intrahepatic bile duct aggregated, abnormal
intrahepatic bile duct decreased branchiness, abnormal
intrahepatic bile duct epithelial cell GFP expression decreased amount, abnormal
intrahepatic bile duct epithelial cell GFP expression spatial pattern, abnormal
liver decreased size, abnormal
liver EGFP expression absent, abnormal
Fig. 4
WT + MO1-id2a
, 
s870Tg + MO1-id2a
liver apoptotic process increased occurrence, abnormal
liver cell population proliferation decreased occurrence, abnormal
Fig. S1
gz15Tg + MO1-id2a
, 
gz15Tg + MO1-id2a + MO4-tp53
liver decreased size, abnormal
liver DsRed expression decreased amount, abnormal
Uribe
et al.
, 2012
Fig. 1
WT + MO1-id2a
eye photoreceptor cell differentiation decreased process quality, abnormal
retina cell decreased amount, abnormal
retina cell population proliferation process quality, abnormal
Fig. 2
WT + MO1-id2a
amacrine cell ab-5e11 labeling absent, abnormal
amacrine cell absent, abnormal
amacrine cell differentiation arrested, abnormal
retinal cone cell absent, abnormal
retinal cone cell differentiation arrested, abnormal
retinal cone cell zpr-1 labeling absent, abnormal
Fig. 3
WT + MO1-id2a
retina
ascl1a
expression increased amount, abnormal
retina
ascl1a
expression increased distribution, abnormal
retina
dla
expression increased amount, abnormal
retina
dla
expression increased distribution, abnormal
retina
dlc
expression increased amount, abnormal
retina
her4.1
expression increased amount, abnormal
retina
hes6
expression increased amount, abnormal
retina
notch1a
expression increased amount, abnormal
retina
notch1a
expression increased distribution, abnormal
Fig. 4
WT + MO1-id2a
eye cell decreased amount, abnormal
eye decreased size, abnormal
retina cell population proliferation process quality, abnormal
Fig. 5
WT + MO1-id2a
amacrine cell absent, abnormal
camera-type eye photoreceptor cell differentiation disrupted, abnormal
retinal cone cell absent, abnormal
Fig. 7
WT + MO1-id2a
retina
ccnd1
expression increased amount, abnormal
retina
cdk6
expression increased amount, abnormal
retina
cdkn1a
expression increased amount, abnormal
retina
fzd6
expression increased amount, abnormal
retina
rspo1
expression increased amount, abnormal
retina
skp2
expression increased amount, abnormal
retina
tcf7l1b
expression increased amount, abnormal
Uribe
et al.
, 2010
Fig. 1
WT + MO1-id2a
brain decreased size, abnormal
eye decreased size, abnormal
retina layer formation disrupted, abnormal
retinal inner nuclear layer unstructured, abnormal
retinal outer nuclear layer unstructured, abnormal
Fig. 2
WT + MO1-id2a
amacrine cell absent, abnormal
camera-type eye photoreceptor cell differentiation disrupted, abnormal
Muller cell decreased amount, abnormal
retinal bipolar neuron absent, abnormal
retinal bipolar neuron differentiation disrupted, abnormal
retinal cone cell absent, abnormal
retinal inner nuclear layer cell undifferentiated, abnormal
retinal outer nuclear layer cell undifferentiated, abnormal
retinal rod cell decreased amount, abnormal
Fig. 4
WT + MO1-id2a
embryonic retina morphogenesis in camera-type eye delayed, abnormal
regulation of neural retina development disrupted, abnormal
Fig. 5
WT + MO1-id2a
embryonic retina morphogenesis in camera-type eye delayed, abnormal
eye decreased size, abnormal
S phase delayed, abnormal
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