Gene

id2a

ID
ZDB-GENE-020910-1
Name
inhibitor of DNA binding 2a
Symbol
id2a Nomenclature History
Previous Names
  • id2
  • cb321 (1)
  • wu:fa04e03
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have protein dimerization activity. Involved in several processes, including intra-S DNA damage checkpoint; regulation of Notch signaling pathway; and regulation of cell proliferation involved in compound eye morphogenesis. Predicted to localize to nucleus. Is expressed in several structures, including brain; eye; immature eye; mesoderm; and neural crest. Orthologous to human ID2 (inhibitor of DNA binding 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
34 figures from 15 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
14 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With id2a Human Ortholog
No data available
Associated With id2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Family IPR026052 DNA-binding protein inhibitor
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length DNA-binding protein inhibitor Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain
UniProtKB:Q7SZQ2 137
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA id2a-201 (1) Ensembl 1,524 nt
mRNA id2a-202 (1) Ensembl 908 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations