| ZFIN ID: ZDB-EXP-230816-9 |
Experiment Conditions Description: transection: caudal fin, chemical treatment by injection: clodronic acid
| transection: caudal fin |
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| Name: | transection |
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| Synonyms: | |
| Definition: | Cutting transversly of an organ or tissue. Type of cutting often used to divide the spinal cord to investigate neural regeneration in zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000181] |
| Name: | caudal fin |
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| Synonyms: | tail, tail fin |
| Definition: | Fin that is the most posterior median fin. It is composed of a complex of three modified centra and modified neural and hemal arches and spines. |
| Ontology: | Anatomy Ontology [ZFA:0001058] |
| chemical treatment by injection: clodronic acid |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | clodronic acid |
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| Synonyms: | (Dichloro-phosphono-methyl)-phosphonic acid, (dichloromethanediyl)bis(phosphonic acid), (dichloromethylene)bisphosphonic acid, (dichloromethylene)diphosphonic acid, acide clodronique, acido clodronico, acidum clodronicum, clodronate, clodronic acid, clodronsaeure, dichloromethylene-1,1-bisphosphonic acid, dichloromethylene-1,1-diphosphonic acid, dichloromethylidene diphosphonate |
| Definition: | An organochlorine compound that is methylene chloride in which both hydrogens are replaced by phosphonic acid groups. It inhibits bone resorption and soft tissue calcification, and is used (often as the disodium salt tetrahydrate) as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteolytic lesions and bone pain associated with skeletal metastases. |
| Ontology: | ChEBI [CHEBI:110423] ( EBI ) |
| Publication: | Kulkarni et al., 2021 |
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