ZFIN ID: ZDB-EXP-180607-1
Experiment Conditions Description: chemical treatment by environment: RF9
chemical treatment by environment: RF9
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: RF9
Synonyms: 1-adamantanecarbonyl-Arg-Phe-NH2, N(2)-(tricyclo[3.3.1.1(3,7)]decan-1-ylcarbonyl)-L-arginyl-L-phenylalaninamide, neuropeptide FF receptor antagonist, NPFF receptor antagonist, RF 9, RF-9
Definition: A dipeptide formed from L-arginine and L-phenylalaninamide residues in which a hydrogen attached to the nitrogen of the alpha-amino group of the arginine residue has been replaced by a 1-adamantanecarbonyl group. It has been reported to be a potent and selective antagonist of neuropeptide FF (NPFF) receptors, but more recently found to be an agonist at both NPFF1R and the kisspeptin receptor (KISS1R).
Ontology: ChEBI [CHEBI:140980]  ( EBI )
Publication: Lee et al., 2017