Search Ontology:
ChEBI

RF9

Term ID
CHEBI:140980
Synonyms
  • 1-adamantanecarbonyl-Arg-Phe-NH2
  • N(2)-(tricyclo[3.3.1.1(3,7)]decan-1-ylcarbonyl)-L-arginyl-L-phenylalaninamide
  • neuropeptide FF receptor antagonist
  • NPFF receptor antagonist
  • RF 9
  • RF-9
Definition
A dipeptide formed from L-arginine and L-phenylalaninamide residues in which a hydrogen attached to the nitrogen of the alpha-amino group of the arginine residue has been replaced by a 1-adamantanecarbonyl group. It has been reported to be a potent and selective antagonist of neuropeptide FF (NPFF) receptors, but more recently found to be an agonist at both NPFF1R and the kisspeptin receptor (KISS1R).
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from RF9
Phenotype where environments contain RF9
Phenotype modified by environments containing RF9
Human Disease Model
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