| ZFIN ID: ZDB-EXP-150603-19 |
Experiment Conditions Description: perforation: retina, chemical treatment: PI-103
| perforation: retina |
|---|
| Name: | perforation |
|---|---|
| Synonyms: | |
| Definition: | Experimental condition in which a hole or break in the membranes of an organ or structure of the body is created. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000178] |
| Name: | retina |
|---|---|
| Synonyms: | retinas |
| Definition: | Multi-tissue structure that contains the retinal neural layer and the retinal pigmented epithelium, and develops from the optic cup. |
| Ontology: | Anatomy Ontology [ZFA:0000152] |
| chemical treatment: PI-103 |
|---|
| Name: | chemical treatment |
|---|---|
| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | PI-103 |
|---|---|
| Synonyms: | 3-[4-(morpholin-4-yl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol, pi-103, PIK-103 |
| Definition: | An organic heterotricyclic compound that is pyrido[3',2':4,5]furo[3,2-d]pyrimidine substituted at positions 2 and 4 by 3-hydroxyphenyl and morpholin-4-yl groups respectively. A dual-kinase inhibitor with anti-cancer properties. |
| Ontology: | ChEBI [CHEBI:90524] ( EBI ) |
| Publication: | Wan et al., 2014 |
|---|