Transgenic Construct
Tg(sod1:sod1_G93R,hsp70l:DsRed)
- ID
- ZDB-TGCONSTRCT-101006-2
- Name
- Tg(sod1:sod1_G93R,hsp70l:DsRed)
- Previous Names
-
- Tg(sod1:sod1G93R,hsp70l:DsRed)
- Tg(sod1:sod1G93R; hsp70:DsRed) (1)
- Type
- engineered_plasmid
- Regulatory Regions
- Coding Sequences
- [Em λ][Ex λ]
- Fpbase:DsRed
- Contains Sequences
- None
- Note
-
In this construct, zebrafish sod1 promoter drives engineered mutant zebrafish sod1 in which glycine 93 has been replaced by arginine (G93R); this mutation affects a conserved amino acid that is often mutated in FALS ( http://alsod.iop.kcl.ac.uk ) (Elshafey et al., 1994, PMID: 8004110 ) -- Ramesh et al. (2010) ZDB-PUB-100601-15
Plasmid Map
None
Genomic Features
That Utilize Tg(sod1:sod1_G93R,hsp70l:DsRed) Construct
Transgenics
That Utilize Tg(sod1:sod1_G93R,hsp70l:DsRed) Construct
| Fish | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|
| gdf6as327/s327; os10Tg |
Fig. 5
from
DuVal et al., 2014
|
||
| os10Tg |
|
15 figures
from
3 publications
|
6 figures
from
2 publications
|
| os10Tg (AB) |
|
Fig. 2 from McGown et al., 2016 | |
| os10Tg/+ |
|
9 figures
from
Benedetti et al., 2016
|
2 figures
from
Benedetti et al., 2016
|
| os10Tg/+ (AB) |
|
||
| os6Tg |
|
8 figures
from
3 publications
|
Fig. 1 from McGown et al., 2013 |
| os6Tg; zf147Tg |
|
Fig. 5 from Goldshtein et al., 2020 |
Sequence Information
Other Construct Pages
None
Citations