Transgenic Construct
Tg(hsp70l:acvr1b_K234R-GFP)
- ID
- ZDB-TGCONSTRCT-071212-1
- Name
- Tg(hsp70l:acvr1b_K234R-GFP)
- Previous Names
-
- hsp:Alk4DN-GFP (1)
- Tg(hsp70l:acvr1b(K234R)-GFP)
- Type
- engineered_plasmid
- Regulatory Regions
- Coding Sequences
- Contains Sequences
- None
- Note
-
The coding sequence for acvr1b has a point mutation to replace lysine 234 with arginine, which is predicted to delete kinase function. This results in a dominant-negative acvr1b receptor.
Plasmid Map
None
Genomic Features
That Utilize Tg(hsp70l:acvr1b_K234R-GFP) Construct
| Genomic Feature | Affected Genomic Regions |
|---|---|
| zf54Tg |
Transgenics
That Utilize Tg(hsp70l:acvr1b_K234R-GFP) Construct
| Fish | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|
| zf54Tg |
|
Fig. S2
from
Jazwinska et al., 2007
|
Sequence Information
Other Construct Pages
None
Citations