TALEN

TALEN1-cyp17a1

ID

ZDB-TALEN-241108-1

Name

TALEN1-cyp17a1

Previous Names

None

Target

cyp17a1 (1)

Target Sequence 1

5' - CTTTCAGGACCTGCAGAAGA - 3'

Target Sequence 2

5' - CCCTCATGATGGGCTCCCAC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ihb144	cyp17a1

Expression

Gene expression in Wild Types + TALEN1-cyp17a1

No data available

Phenotype

Phenotype resulting from TALEN1-cyp17a1

No data available

Phenotype of all Fish created by or utilizing TALEN1-cyp17a1

Phenotype	Fish	Conditions	Figures
whole organism lipid increased amount, abnormal	cyp17a1^{ihb144/ihb144}	standard conditions	Fig. 6 from Shi et al., 2019
aerobic respiration increased rate, abnormal	cyp17a1^{ihb144/ihb144}	standard conditions	Fig. 6 from Shi et al., 2019
blood plasma progesterone increased amount, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 1 from Zhai et al., 2018
male organism blood lhb expression increased amount, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 5 from Zhai et al., 2018
female sex determination occurrence, ameliorated	cyp17a1^{ihb144/ihb144} (AB)	chemical treatment by environment: estradiol	Fig. 4 from Zhai et al., 2018
testis hypertrophic, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 6, Fig. 7 from Zhai et al., 2018
female organism absent, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 1 from Zhai et al., 2018
female sex determination arrested, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 1, Fig. 4 from Zhai et al., 2018
ovary absent, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 3, Fig. 4 from Zhai et al., 2018
male organism increased amount, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 1 from Zhai et al., 2018
male organism blood fshb expression increased amount, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 5 from Zhai et al., 2018
female sex determination occurrence, ameliorated	cyp17a1^{ihb144/ihb144} (AB)	chemical treatment by environment: testosterone	Fig. 4 from Zhai et al., 2018
male organism hypophysis lhb expression increased amount, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 5, Fig. 6 from Zhai et al., 2018
testis igf3 expression increased amount, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 5, Fig. 6 from Zhai et al., 2018
testis (20R)-17,20-dihydroxypregn-4-en-3-one increased amount, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 1 from Zhai et al., 2018
male organism hypophysis cga expression increased amount, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 5 from Zhai et al., 2018
male sex determination increased occurrence, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 1 from Zhai et al., 2018
blood plasma estradiol decreased amount, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 1 from Zhai et al., 2018
ovary present, ameliorated	cyp17a1^{ihb144/ihb144} (AB)	chemical treatment by environment: estradiol	Fig. 4 from Zhai et al., 2018
testis insl3 expression increased amount, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 5, Fig. 6 from Zhai et al., 2018
sperm increased amount, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 6, Fig. 7 from Zhai et al., 2018
male mating behavior decreased occurrence, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 2 from Zhai et al., 2018
ovary present, ameliorated	cyp17a1^{ihb144/ihb144} (AB)	chemical treatment by environment: testosterone	Fig. 4 from Zhai et al., 2018
testis apoptotic process increased occurrence, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 3 from Zhai et al., 2018
male organism hypophysis fshb expression increased amount, abnormal	cyp17a1^{ihb144/ihb144} (AB)	standard conditions	Fig. 5, Fig. 6 from Zhai et al., 2018
sperm amount, ameliorated	cyp17a1^{ihb144/ihb144}; fshb^{ihb351/ihb351}	standard conditions	Fig. 7 from Zhai et al., 2018
testis size, ameliorated	cyp17a1^{ihb144/ihb144}; fshb^{ihb351/ihb351}	standard conditions	Fig. 7 from Zhai et al., 2018
aerobic respiration decreased rate, abnormal	cyp17a1^{ihb144/ihb144}; pomca^{ihb408/ihb408}	standard conditions	Fig. 6 from Shi et al., 2019
whole organism lipid increased amount, ameliorated	cyp17a1^{ihb144/ihb144}; pomca^{ihb408/ihb408}	standard conditions	Fig. 6 from Shi et al., 2019

Citations