TALEN

TALEN1-bag3

ID
ZDB-TALEN-200320-1
Name
TALEN1-bag3
Previous Names
None
Target
Target Sequence 1
5' - TGTCATGAAAACCCTGAA - 3'
ZFIN BLAST NCBI BLAST Ensembl
Target Sequence 2
5' - TGTAGGAGAAACTAGGAT - 3'
ZFIN BLAST NCBI BLAST Ensembl
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
xu083 bag3
Expression
Gene expression in Wild Types + TALEN1-bag3
No data available
Phenotype
Phenotype resulting from TALEN1-bag3
No data available
Phenotype of all Fish created by or utilizing TALEN1-bag3
Phenotype Fish Conditions Figures
cardiac muscle cell apoptotic, abnormal bag3xu083/xu083 standard conditions Fig. 3. with image from Ding et al., 2019
heart myh7 expression increased amount, abnormal bag3xu083/xu083 standard conditions Fig. 3. with image from Ding et al., 2019
cardiac ventricle increased area, abnormal bag3xu083/xu083 standard conditions Fig. 3. with image from Ding et al., 2019
heart decreased functionality, abnormal bag3xu083/xu083 standard conditions Fig. 2. with image from Ding et al., 2019
whole organism decreased life span, abnormal bag3xu083/xu083 standard conditions Fig. 1 from Ding et al., 2019
whole organism decreased mass, abnormal bag3xu083/xu083 standard conditions Fig. 1 from Ding et al., 2019
heart nppb expression increased amount, abnormal bag3xu083/xu083 standard conditions Fig. 3. with image from Ding et al., 2019
heart Ab11-map1lc3 labeling decreased amount, abnormal bag3xu083/xu083 standard conditions Fig. 7 with image from Ding et al., 2022
cardiac muscle myoblast decreased amount, abnormal bag3xu083/xu083 standard conditions Fig. 3 with image from Ding et al., 2022
myocardium decreased functionality, abnormal bag3xu083/xu083 standard conditions Fig. 2. with image from Ding et al., 2019
cardiac ventricle decreased functionality, abnormal bag3xu083/xu083 standard conditions Fig. 2. with image from Ding et al., 2019
heart protein ubiquitination increased occurrence, abnormal bag3xu083/xu083 standard conditions Fig. 3 with image,  Fig. 5 with image from Ding et al., 2022
cardiac muscle cell contraction decreased process quality, abnormal bag3xu083/xu083 standard conditions Fig. 3. with image from Ding et al., 2019
heart Ab6-ub labeling increased amount, abnormal bag3xu083/xu083 standard conditions Fig. 5. with image from Ding et al., 2019
cardiac muscle cell degeneration, abnormal bag3xu083/xu083 standard conditions Fig. 3. with image,  Fig. 5. with image from Ding et al., 2019
cardiac ventricle anatomical surface increased area, abnormal bag3xu083/xu083 standard conditions Fig. 5 with image,  Fig. 6 with image,  Fig. 7 with image from Ding et al., 2022
cardiac muscle cell decreased amount, abnormal bag3xu083/xu083 standard conditions Fig. 3. with image,  Fig. 5. with image from Ding et al., 2019
swimming behavior decreased linear velocity, abnormal bag3xu083/xu083 standard conditions Fig. 1 from Ding et al., 2019
heart nppa expression decreased amount, abnormal bag3xu083/xu083 standard conditions Fig. 3. with image from Ding et al., 2019
heart ab1-map1lc3 labeling decreased amount, abnormal bag3xu083/xu083 standard conditions Fig. 4. with image,  Fig. 5. with image from Ding et al., 2019
heart muscle cell degeneration, abnormal bag3xu083/xu083 standard conditions Fig. 3. with image from Ding et al., 2019
heart ab1-eif4ebp1 labeling decreased amount, abnormal bag3xu083/xu083 standard conditions Fig. 4. with image from Ding et al., 2019
heart contraction increased duration, abnormal bag3xu083/xu083 standard conditions Fig. 2. with image from Ding et al., 2019
trabecular layer of ventricle decreased mass density, abnormal bag3xu083/xu083 standard conditions Fig. 3 with image,  Fig. 5 with image from Ding et al., 2022
Fig. 3. with image from Ding et al., 2019
heart mitochondrion swollen, abnormal bag3xu083/xu083 standard conditions Fig. 3. with image,  Fig. 5. with image from Ding et al., 2019
cardiac ventricle increased size, abnormal bag3xu083/xu083 standard conditions Fig. 3. with image from Ding et al., 2019
cardiac muscle myoblast mitochondrion swollen, abnormal bag3xu083/xu083 standard conditions Fig. 3 with image,  Fig. 5 with image,  Fig. 6 with image from Ding et al., 2022
heart contraction decreased process quality, abnormal bag3xu083/xu083 standard conditions Fig. 2. with image from Ding et al., 2019
heart ab1-rps6 labeling increased amount, abnormal bag3xu083/xu083 standard conditions Fig. 4. with image,  Fig. 5. with image from Ding et al., 2019
heart muscle cell decreased amount, abnormal bag3xu083/xu083 standard conditions Fig. 3. with image from Ding et al., 2019
heart contraction decreased efficacy, abnormal bag3xu083/xu083 standard conditions Fig. 1 with image,  Fig. 3 with image,  Fig. 6 with image,  Fig. 7 with image from Ding et al., 2022
myocardium vacuolated, abnormal bag3xu083/xu083 standard conditions Fig. 3. with image from Ding et al., 2019
heart protein ubiquitination increased occurrence, abnormal bag3xu083/+ standard conditions Fig. 2 with image from Ding et al., 2022
cardiac ventricle lipid increased amount, abnormal bag3xu083/+ standard conditions Fig. 2 with image from Ding et al., 2022
heart contraction decreased efficacy, abnormal bag3xu083/xu083 + CRISPR1-atxn2l standard conditions Fig. 6 with image from Ding et al., 2022
heart contraction decreased efficacy, abnormal bag3xu083/xu083 + CRISPR1-ddit4 standard conditions Fig. 6 with image from Ding et al., 2022
cardiac muscle myoblast mitochondrion swollen, abnormal bag3xu083/xu083 + CRISPR1-dnajb6b standard conditions Fig. 5 with image from Ding et al., 2022
heart dnajb6b expression decreased amount, abnormal bag3xu083/xu083 + CRISPR1-dnajb6b standard conditions Fig. 4 with image from Ding et al., 2022
heart protein ubiquitination increased occurrence, exacerbated bag3xu083/xu083 + CRISPR1-dnajb6b standard conditions Fig. 5 with image from Ding et al., 2022
heart contraction decreased efficacy, abnormal bag3xu083/xu083 + CRISPR1-dnajb6b standard conditions Fig. 4 with image from Ding et al., 2022
trabecular layer of ventricle decreased mass density, exacerbated bag3xu083/xu083 + CRISPR1-dnajb6b standard conditions Fig. 5 with image from Ding et al., 2022
cardiac ventricle anatomical surface increased area, abnormal bag3xu083/xu083 + CRISPR1-dnajb6b standard conditions Fig. 5 with image from Ding et al., 2022
cardiac muscle myoblast decreased amount, abnormal bag3xu083/xu083 + CRISPR1-dnajb6b standard conditions Fig. 5 with image from Ding et al., 2022
cardiac ventricle lipid increased amount, abnormal bag3xu083/xu083 + CRISPR1-dnajb6b standard conditions Fig. 5 with image from Ding et al., 2022
heart contraction decreased efficacy, abnormal bag3xu083/xu083 + CRISPR1-pik3r1 standard conditions Fig. 6 with image from Ding et al., 2022
heart contraction decreased efficacy, abnormal bag3xu083/xu083 + CRISPR1-rab11fip3 standard conditions Fig. 6 with image from Ding et al., 2022
heart contraction decreased efficacy, abnormal bag3xu083/xu083 + CRISPR1-snrkb standard conditions Fig. 6 with image from Ding et al., 2022
heart contraction decreased efficacy, abnormal bag3xu083/xu083 + CRISPR1-ulk2 standard conditions Fig. 6 with image from Ding et al., 2022
trabecular layer of ventricle normal mass density, ameliorated bag3xu083/xu083 + CRISPR2-mtor standard conditions Fig. 3 with image from Ding et al., 2022
cardiac muscle myoblast mitochondrion normal size, ameliorated bag3xu083/xu083 + CRISPR2-mtor standard conditions Fig. 3 with image from Ding et al., 2022
cardiac muscle myoblast normal amount, ameliorated bag3xu083/xu083 + CRISPR2-mtor standard conditions Fig. 3 with image from Ding et al., 2022
heart contraction process efficacy, ameliorated bag3xu083/xu083 + CRISPR2-mtor standard conditions Fig. 3 with image from Ding et al., 2022
heart protein ubiquitination normal occurrence, ameliorated bag3xu083/xu083 + CRISPR2-mtor standard conditions Fig. 3 with image from Ding et al., 2022
heart contraction decreased efficacy, abnormal bag3xu083/xu083 + CRISPR4-acta1a standard conditions Fig. 6 with image from Ding et al., 2022
heart contraction decreased efficacy, exacerbated bag3xu083/xu083 + CRISPR5-myh9b standard conditions Fig. 6 with image from Ding et al., 2022
cardiac muscle myoblast mitochondrion swollen, abnormal bag3xu083/xu083 + CRISPR5-myh9b standard conditions Fig. 6 with image from Ding et al., 2022
cardiac ventricle increased size, exacerbated bag3xu083/xu083 + CRISPR5-myh9b standard conditions Fig. 6 with image from Ding et al., 2022
cardiac muscle Z disc aggregated, abnormal bag3xu083/xu083 + CRISPR5-myh9b standard conditions Fig. 6 with image from Ding et al., 2022
cardiac muscle myoblast mitochondrion swollen, abnormal bag3xu083/+; dnajb6bxu0411Gt/xu0411Gt standard conditions Fig. 2 with image from Ding et al., 2022
whole organism viability, abnormal bag3xu083/+; dnajb6bxu0411Gt/xu0411Gt standard conditions Fig. 2 with image from Ding et al., 2022
heart contraction decreased efficacy, abnormal bag3xu083/+; dnajb6bxu0411Gt/xu0411Gt standard conditions Fig. 2 with image from Ding et al., 2022
heart protein ubiquitination increased occurrence, exacerbated bag3xu083/+; dnajb6bxu0411Gt/xu0411Gt standard conditions Fig. 2 with image from Ding et al., 2022
cardiac ventricle lipid increased amount, exacerbated bag3xu083/+; dnajb6bxu0411Gt/xu0411Gt standard conditions Fig. 2 with image from Ding et al., 2022
cardiac muscle myoblast decreased amount, abnormal bag3xu083/+; dnajb6bxu0411Gt/xu0411Gt standard conditions Fig. 2 with image from Ding et al., 2022
cardiac ventricle anatomical surface increased area, abnormal bag3xu083/+; dnajb6bxu0411Gt/xu0411Gt standard conditions Fig. 2 with image from Ding et al., 2022
heart contraction decreased efficacy, abnormal bag3xu083/xu083; ano5amn0136Gt/mn0136Gt standard conditions Fig. 1 with image from Ding et al., 2022
whole organism viability, abnormal bag3xu083/xu083; dnajb6bxu0411Gt/xu0411Gt standard conditions Fig. 1 with image from Ding et al., 2022
cardiac ventricle increased size, abnormal bag3xu083/xu083; dnajb6bxu0411Gt/xu0411Gt standard conditions Fig. 1 with image from Ding et al., 2022
heart contraction decreased efficacy, abnormal bag3xu083/xu083; dnajb6bxu0411Gt/xu0411Gt standard conditions Fig. 1 with image from Ding et al., 2022
whole organism decreased life span, ameliorated bag3xu083/xu083; mtorxu015Gt/+ standard conditions Fig. 5. with image from Ding et al., 2019
cardiac ventricle decreased functionality, ameliorated bag3xu083/xu083; mtorxu015Gt/+ standard conditions Fig. 5. with image from Ding et al., 2019
cardiac muscle cell degeneration, ameliorated bag3xu083/xu083; mtorxu015Gt/+ standard conditions Fig. 5. with image from Ding et al., 2019
heart mitochondrion swollen, ameliorated bag3xu083/xu083; mtorxu015Gt/+ standard conditions Fig. 5. with image from Ding et al., 2019
myocardium vacuolated, ameliorated bag3xu083/xu083; mtorxu015Gt/+ standard conditions Fig. 5. with image from Ding et al., 2019
cardiac muscle cell contraction decreased process quality, ameliorated bag3xu083/xu083; mtorxu015Gt/+ standard conditions Fig. 5. with image from Ding et al., 2019
heart ab1-map1lc3 labeling increased amount, abnormal bag3xu083/xu083; mtorxu015Gt/+ standard conditions Fig. 5. with image from Ding et al., 2019
cardiac muscle cell decreased amount, ameliorated bag3xu083/xu083; mtorxu015Gt/+ standard conditions Fig. 5. with image from Ding et al., 2019
heart Ab11-map1lc3 labeling decreased amount, abnormal bag3xu083/xu083; myh9bzf3748/+ standard conditions Fig. 7 with image from Ding et al., 2022
heart contraction decreased efficacy, exacerbated bag3xu083/xu083; myh9bzf3748/+ standard conditions Fig. 7 with image from Ding et al., 2022
cardiac muscle Z disc aggregated, abnormal bag3xu083/xu083; myh9bzf3748/+ standard conditions Fig. 7 with image from Ding et al., 2022
cardiac ventricle anatomical surface increased area, exacerbated bag3xu083/xu083; myh9bzf3748/+ standard conditions Fig. 7 with image from Ding et al., 2022
heart contraction decreased efficacy, abnormal bag3xu083/xu083; rxraaxu0419Gt/xu0419Gt standard conditions Fig. 1 with image from Ding et al., 2022
heart contraction decreased efficacy, abnormal bag3xu083/xu083; sorbs2bmn0002Gt/mn0002Gt standard conditions Fig. 1 with image from Ding et al., 2022
Citations
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