TALEN

TALEN2-lft2

ID
ZDB-TALEN-180417-4
Name
TALEN2-lft2
Previous Names
None
Target
Target Sequence 1
5' - TTCATCCAGCTGTTCATTTT - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Target Sequence 2
5' - TGCTGGAATCCCTGTGTGAG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
a146 lft2
Expression
Gene expression in Wild Types + TALEN2-lft2
No data available
Phenotype
Phenotype resulting from TALEN2-lft2
No data available
Phenotype of all Fish created by or utilizing TALEN2-lft2
Phenotype Fish Conditions Figures
endoderm sox17 expression spatial pattern, abnormal lft2a146/a146 standard conditions Fig. 1 with image from Norris et al., 2017
endodermal cell increased amount, abnormal lft2a146/a146 standard conditions Fig. 1 with image from Norris et al., 2017
endoderm sox17 expression increased amount, abnormal lft2a146/a146 standard conditions Fig. 1 with image from Norris et al., 2017
endoderm sox17 expression increased distribution, abnormal lft2a146/a146 standard conditions Fig. 1 with image from Norris et al., 2017
caudal fin mesenchyme morphology, abnormal apelaa141/a141; lft2a146/a146 standard conditions Fig. 2 with image from Norris et al., 2017
ventral fin fold mesenchyme morphology, abnormal apelaa141/a141; lft2a146/a146 standard conditions Fig. 2 with image from Norris et al., 2017
heart decreased width, abnormal apelaa141/a141; lft2a146/a146 standard conditions Fig. 2 with image from Norris et al., 2017
blood increased accumulation caudal fin, abnormal apelaa141/a141; lft2a146/a146 standard conditions Fig. 2 with image from Norris et al., 2017
endodermal cell increased amount, abnormal apelaa141/a141; lft2a146/a146 standard conditions Fig. 1 with image from Norris et al., 2017
endoderm sox17 expression spatial pattern, abnormal apelaa141/a141; lft2a146/a146 standard conditions Fig. 1 with image from Norris et al., 2017
heart decreased size, abnormal apelaa141/a141; lft2a146/a146 standard conditions Fig. 2 with image from Norris et al., 2017
endoderm sox17 expression decreased distribution, abnormal apelaa141/a141; lft2a146/a146 standard conditions Fig. 1 with image from Norris et al., 2017
caudal fin blood circulation decreased occurrence, abnormal apelaa141/a141; lft2a146/a146 standard conditions Fig. 2 with image from Norris et al., 2017
caudal fin morphology, abnormal apelaa141/a141; lft2a146/a146 standard conditions Fig. 2 with image from Norris et al., 2017
endoderm sox17 expression spatial pattern, abnormal lft2a146/a146; apelaa142/a142 standard conditions Fig. 1 with image from Norris et al., 2017
caudal fin mesenchyme morphology, abnormal lft2a146/a146; apelaa142/a142 standard conditions Fig. 2 with image from Norris et al., 2017
ventral fin fold mesenchyme morphology, abnormal lft2a146/a146; apelaa142/a142 standard conditions Fig. 2 with image from Norris et al., 2017
heart decreased width, abnormal lft2a146/a146; apelaa142/a142 standard conditions Fig. 2 with image from Norris et al., 2017
blood increased accumulation caudal fin, abnormal lft2a146/a146; apelaa142/a142 standard conditions Fig. 2 with image from Norris et al., 2017
endodermal cell increased amount, abnormal lft2a146/a146; apelaa142/a142 standard conditions Fig. 1 with image from Norris et al., 2017
heart decreased size, abnormal lft2a146/a146; apelaa142/a142 standard conditions Fig. 2 with image from Norris et al., 2017
endoderm sox17 expression decreased distribution, abnormal lft2a146/a146; apelaa142/a142 standard conditions Fig. 1 with image from Norris et al., 2017
caudal fin blood circulation decreased occurrence, abnormal lft2a146/a146; apelaa142/a142 standard conditions Fig. 2 with image from Norris et al., 2017
caudal fin morphology, abnormal lft2a146/a146; apelaa142/a142 standard conditions Fig. 2 with image from Norris et al., 2017
margin ndr1 expression increased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
endoderm sox32 expression increased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3 with image,  Fig. 4 with image,  Fig. 6 with image,  Fig. 6-S3 with image from Rogers et al., 2017
axis bifurcated, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 1-S2 with image from Rogers et al., 2017
axis lft2 expression spatial pattern, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
axis lft2 expression increased distribution, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
axis noto expression spatial pattern, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 4 with image,  Fig. 6 with image,  Fig. 6-S3 with image from Rogers et al., 2017
axis lft1 expression spatial pattern, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
mesoderm noto expression spatial pattern, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3 with image from Rogers et al., 2017
presumptive mesoderm noto expression increased distribution, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3 with image from Rogers et al., 2017
axis lft2 expression increased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
heart tube aplastic, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 1-S1 with image from Rogers et al., 2017
caudal fin morphology, ameliorated lft2a146/a146; lft1a145/a145 chemical treatment by environment: SB 505124 Fig. 6 with image,  Fig. 6-S1 with image,  Fig. 6-S2 with image from Rogers et al., 2017
endoderm sox32 expression spatial pattern, ameliorated lft2a146/a146; lft1a145/a145 chemical treatment by environment: SB 505124 Fig. 6 with image,  Fig. 6-S3 with image from Rogers et al., 2017
whole organism morphology, ameliorated lft2a146/a146; lft1a145/a145 chemical treatment by environment: SB 505124 Fig. 6 with image,  Fig. 6-S1 with image from Rogers et al., 2017
margin lft1 expression increased distribution, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
axis noto expression amount, ameliorated lft2a146/a146; lft1a145/a145 chemical treatment by environment: SB 505124 Fig. 6 with image,  Fig. 6-S3 with image from Rogers et al., 2017
axis lft1 expression increased distribution, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
embryonic pattern specification decreased process quality, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 1 with image from Rogers et al., 2017
presumptive endoderm sox32 expression spatial pattern, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3 with image from Rogers et al., 2017
margin lft1 expression increased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
presumptive mesoderm noto expression increased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3 with image from Rogers et al., 2017
margin ndr1 expression increased distribution, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
axis noto expression increased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 4 with image,  Fig. 6 with image,  Fig. 6-S3 with image from Rogers et al., 2017
axis lft1 expression increased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
caudal fin curved dorsal, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 6-S1 with image from Rogers et al., 2017
axis ndr2 expression increased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
caudal fin decreased length, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 1 with image,  Fig. 6 with image,  Fig. 6-S1 with image from Rogers et al., 2017
eye morphology, ameliorated lft2a146/a146; lft1a145/a145 chemical treatment by environment: SB 505124 Fig. 6 with image,  Fig. 6-S1 with image,  Fig. 6-S2 with image from Rogers et al., 2017
eye morphology, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 6 with image,  Fig. 6-S1 with image from Rogers et al., 2017
caudal fin morphology, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 1 with image,  Fig. 6 with image,  Fig. 6-S1 with image from Rogers et al., 2017
heart tube myl7 expression absent, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 1-S1 with image from Rogers et al., 2017
endoderm sox32 expression amount, ameliorated lft2a146/a146; lft1a145/a145 chemical treatment by environment: SB 505124 Fig. 6 with image,  Fig. 6-S3 with image from Rogers et al., 2017
whole organism necrotic, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 6 with image from Rogers et al., 2017
margin sox32 expression increased distribution, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 4 with image,  Fig. 6-S3 with image from Rogers et al., 2017
mesoderm noto expression increased distribution, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3 with image from Rogers et al., 2017
margin sox32 expression decreased amount, abnormal lft2a146/a146; lft1a145/a145 chemical treatment by environment: SB 505124 Fig. 6-S3 with image from Rogers et al., 2017
presumptive endoderm sox32 expression increased distribution, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3 with image from Rogers et al., 2017
margin lft2 expression spatial pattern, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
margin lft2 expression increased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
margin lft1 expression spatial pattern, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
whole organism Ab9-smad2 labeling increased distribution, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 2 with image from Rogers et al., 2017
axis ndr2 expression increased distribution, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
margin lft2 expression increased distribution, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
caudal fin aplastic, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 1 with image from Rogers et al., 2017
heart aplastic, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 1 with image from Rogers et al., 2017
caudal fin length, ameliorated lft2a146/a146; lft1a145/a145 chemical treatment by environment: SB 505124 Fig. 6 with image,  Fig. 6-S1 with image,  Fig. 6-S2 with image from Rogers et al., 2017
presumptive endoderm sox32 expression increased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3 with image from Rogers et al., 2017
endoderm sox17 expression spatial pattern, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
margin noto expression decreased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 6-S3 with image from Rogers et al., 2017
axis noto expression spatial pattern, ameliorated lft2a146/a146; lft1a145/a145 chemical treatment by environment: SB 505124 Fig. 6 with image,  Fig. 6-S3 with image from Rogers et al., 2017
whole organism Ab9-smad2 labeling increased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 2 with image,  Fig. 2-S1 with image from Rogers et al., 2017
eye aplastic, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 1 with image,  Fig. 6 with image,  Fig. 6-S1 with image from Rogers et al., 2017
margin sox32 expression increased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
presumptive mesoderm noto expression spatial pattern, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3 with image from Rogers et al., 2017
blastodisc anatomical margin lft1 expression increased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
endoderm sox17 expression increased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
whole organism decreased length, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 6 with image,  Fig. 6-S1 with image from Rogers et al., 2017
mesoderm noto expression increased amount, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3 with image from Rogers et al., 2017
axis noto expression increased distribution, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 4 with image,  Fig. 6 with image,  Fig. 6-S3 with image from Rogers et al., 2017
endoderm sox32 expression spatial pattern, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3 with image,  Fig. 4 with image,  Fig. 6 with image,  Fig. 6-S3 with image from Rogers et al., 2017
endoderm sox32 expression increased distribution, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3 with image,  Fig. 4 with image,  Fig. 6 with image,  Fig. 6-S3 with image from Rogers et al., 2017
whole organism morphology, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 6 with image,  Fig. 6-S1 with image from Rogers et al., 2017
margin sox32 expression spatial pattern, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 4 with image,  Fig. 6-S3 with image from Rogers et al., 2017
endoderm sox17 expression increased distribution, abnormal lft2a146/a146; lft1a145/a145 standard conditions Fig. 3-S1 with image from Rogers et al., 2017
axis curved, abnormal lft2a146/+; ndr1cz35/+; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
axis curved, abnormal lft2a146/+; ndr1cz35/cz35; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
whole organism morphology, abnormal lft2a146/a146; ndr1cz35/+; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
whole organism decreased length, abnormal lft2a146/a146; ndr1cz35/+; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
notochord kinked, abnormal lft2a146/a146; ndr1cz35/+; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
caudal fin curved dorsal, abnormal lft2a146/a146; ndr1cz35/+; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
eye morphology, abnormal lft2a146/a146; ndr1cz35/+; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
eye aplastic, abnormal lft2a146/a146; ndr1cz35/+; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
axis noto expression decreased amount, abnormal lft2a146/a146; ndr1cz35/cz35; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
axis bifurcated, abnormal lft2a146/a146; ndr1cz35/cz35; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
axis noto expression spatial pattern, abnormal lft2a146/a146; ndr1cz35/cz35; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
margin noto expression decreased distribution, abnormal lft2a146/a146; ndr1cz35/cz35; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
margin noto expression spatial pattern, abnormal lft2a146/a146; ndr1cz35/cz35; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
margin noto expression decreased amount, abnormal lft2a146/a146; ndr1cz35/cz35; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
axis noto expression decreased distribution, abnormal lft2a146/a146; ndr1cz35/cz35; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
notochord kinked, abnormal ndr2m294/+; lft2a146/+; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
eye morphology, abnormal ndr2m294/+; lft2a146/+; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
caudal fin decreased length, abnormal ndr2m294/+; lft2a146/a146; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
whole organism morphology, abnormal ndr2m294/+; lft2a146/a146; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
notochord kinked, abnormal ndr2m294/+; lft2a146/a146; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
whole organism decreased length, abnormal ndr2m294/+; lft2a146/a146; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
eye morphology, abnormal ndr2m294/+; lft2a146/a146; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
caudal fin morphology, abnormal ndr2m294/+; lft2a146/a146; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
eye aplastic, abnormal ndr2m294/+; lft2a146/a146; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
notochord kinked, abnormal ndr2m294/m294; lft2a146/+; lft1a145/a145 standard conditions Fig. 4 with image from Rogers et al., 2017
Citations
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