TALEN

TALEN1-zap70

ID

ZDB-TALEN-171030-1

Name

TALEN1-zap70

Previous Names

None

Target

Target Sequence 1

5' - GTTCCTCCTGCGACAGTGC - 3'

Target Sequence 2

5' - CCAGATCATAGACAGCACATA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
y442	zap70

Expression

Gene expression in Wild Types + TALEN1-zap70

No data available

Phenotype

Phenotype resulting from TALEN1-zap70

No data available

Phenotype of all Fish created by or utilizing TALEN1-zap70

Phenotype	Fish	Conditions	Figures
T cell trbc1 expression absent, abnormal	zap70^y442/y442; sd2Tg; y1Tg	standard conditions	Fig. 3 from Moore et al., 2016
T cell lck expression absent, abnormal	zap70^y442/y442; sd2Tg; y1Tg	standard conditions	Fig. 3 from Moore et al., 2016
head kidney lymphocyte decreased amount, abnormal	zap70^y442/y442; sd2Tg; y1Tg	standard conditions	Fig. 3 from Moore et al., 2016
T cell absent, abnormal	zap70^y442/y442; sd2Tg; y1Tg	standard conditions	Fig. 3 from Moore et al., 2016
thymus decreased size, abnormal	zap70^y442/y442; sd2Tg; y1Tg	standard conditions	Fig. 3 from Moore et al., 2016
T cell trac expression absent, abnormal	zap70^y442/y442; sd2Tg; y1Tg	standard conditions	Fig. 3 from Moore et al., 2016
pro-T cell decreased amount, abnormal	zap70^y442/y442; sd2Tg; y1Tg	standard conditions	Fig. 3 from Moore et al., 2016
T cell il7r expression absent, abnormal	zap70^y442/y442; sd2Tg; y1Tg	standard conditions	Fig. 3 from Moore et al., 2016

Citations