Morpholino

MO2-mecom

ID

ZDB-MRPHLNO-130225-2

Name

MO2-mecom

Previous Names

splicing i2e3 MO (1)

Target

mecom (1)

Sequence

5' - TCAACCCTGCTGATGTTAAACTTCT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Splice-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-mecom

Expressed Gene	Anatomy	Figures
barx1	neurocranium pharyngeal arch 1 pharyngeal arch 2 pharyngeal arch 6 pharyngeal arch 7	Fig. 3 from Ding et al., 2013
dlx2a	pharyngeal arch 1 pharyngeal arch 2 pharyngeal arch 3	Fig. 3 from Ding et al., 2013

Phenotype

Phenotype resulting from MO2-mecom

Phenotype	Fish	Figures
ceratohyal cartilage increased angle to ceratohyal cartilage, abnormal	WT + MO2-mecom	Fig. 2 from Ding et al., 2013
ethmoid cartilage decreased size, abnormal	WT + MO2-mecom	Fig. 2 from Ding et al., 2013
Meckel's cartilage shortened, abnormal	WT + MO2-mecom	Fig. 2 from Ding et al., 2013
neurocranial trabecula shortened, abnormal	WT + MO2-mecom	Fig. 2 from Ding et al., 2013
neurocranium decreased thickness, abnormal	WT + MO2-mecom	Fig. 2 from Ding et al., 2013
palatoquadrate cartilage decreased size, abnormal	WT + MO2-mecom	Fig. 2 from Ding et al., 2013

Phenotype of all Fish created by or utilizing MO2-mecom

Phenotype	Fish	Conditions	Figures
palatoquadrate cartilage decreased size, abnormal	WT + MO2-mecom	standard conditions	Fig. 2 from Ding et al., 2013
Meckel's cartilage shortened, abnormal	WT + MO2-mecom	standard conditions	Fig. 2 from Ding et al., 2013
neurocranial trabecula shortened, abnormal	WT + MO2-mecom	standard conditions	Fig. 2 from Ding et al., 2013
ceratohyal cartilage increased angle to ceratohyal cartilage, abnormal	WT + MO2-mecom	standard conditions	Fig. 2 from Ding et al., 2013
neurocranium decreased thickness, abnormal	WT + MO2-mecom	standard conditions	Fig. 2 from Ding et al., 2013
ethmoid cartilage decreased size, abnormal	WT + MO2-mecom	standard conditions	Fig. 2 from Ding et al., 2013
Meckel's cartilage shortened, abnormal	WT + MO2-mecom + MO2-prdm1a	standard conditions	Fig. 4 from Ding et al., 2013
ethmoid cartilage decreased size, abnormal	WT + MO2-mecom + MO2-prdm1a	standard conditions	Fig. 4 from Ding et al., 2013
embryonic neurocranium morphogenesis disrupted, abnormal	WT + MO2-mecom + MO2-prdm1a	standard conditions	Fig. 4 from Ding et al., 2013
ceratobranchial 5 cartilage absent, abnormal	WT + MO2-mecom + MO2-prdm1a	standard conditions	Fig. 4 from Ding et al., 2013
ceratobranchial 2 cartilage absent, abnormal	WT + MO2-mecom + MO2-prdm1a	standard conditions	Fig. 4 from Ding et al., 2013
neurocranial trabecula shortened, abnormal	WT + MO2-mecom + MO2-prdm1a	standard conditions	Fig. 4 from Ding et al., 2013
ceratobranchial 4 cartilage absent, abnormal	WT + MO2-mecom + MO2-prdm1a	standard conditions	Fig. 4 from Ding et al., 2013
embryonic viscerocranium morphogenesis disrupted, abnormal	WT + MO2-mecom + MO2-prdm1a	standard conditions	Fig. 4 from Ding et al., 2013
ceratobranchial 3 cartilage absent, abnormal	WT + MO2-mecom + MO2-prdm1a	standard conditions	Fig. 4 from Ding et al., 2013
neurocranium decreased thickness, abnormal	WT + MO2-mecom + MO2-prdm1a	standard conditions	Fig. 4 from Ding et al., 2013
neurocranial trabecula shortened, abnormal	WT + MO2-mecom + MO2-prdm16	standard conditions	Fig. 2 from Ding et al., 2013
neurocranium decreased thickness, abnormal	WT + MO2-mecom + MO2-prdm16	standard conditions	Fig. 2 from Ding et al., 2013
embryonic neurocranium morphogenesis disrupted, abnormal	WT + MO2-mecom + MO2-prdm16	standard conditions	Fig. 2 from Ding et al., 2013
ethmoid cartilage decreased size, abnormal	WT + MO2-mecom + MO2-prdm16	standard conditions	Fig. 2 from Ding et al., 2013

Citations