Morpholino

MO1-mnx1

ID

ZDB-MRPHLNO-111028-1

Name

MO1-mnx1

Previous Names

None

Target

mnx1 (1)

Sequence

5' - AACAGATTAACGCCTCGTTCGTAAC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Translation-blocking MO targeted to 5-prime UTR of mnx1.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-mnx1

Expressed Gene	Anatomy	Figures
arxa	posterior pancreatic bud pancreatic A cell	Fig. S6 from Dalgin et al., 2011
gcga	posterior pancreatic bud pancreatic A cell	Fig. 4 , Fig. 7 from Dalgin et al., 2011
ins	endocrine pancreas pancreatic B cell posterior pancreatic bud pancreatic B cell	Fig. 2 , Fig. 4 , Fig. 5 , Fig. 7 from Dalgin et al., 2011
isl1a	posterior pancreatic bud	Fig. 2 from Dalgin et al., 2011
myod1	somite	Fig. 3 from Dalgin et al., 2011
neurod1	endoderm endocrine cell	Fig. 3 from Dalgin et al., 2011
sst1.1	posterior pancreatic bud D cell	Fig. 4 from Dalgin et al., 2011

Phenotype

Phenotype resulting from MO1-mnx1

Phenotype	Fish	Figures
endocrine pancreas has extra parts of type pancreatic A cell, abnormal	nl1Tg + MO1-mnx1	Fig. 5 from Dalgin et al., 2011
endocrine pancreas has fewer parts of type pancreatic B cell, abnormal	nl1Tg + MO1-mnx1	Fig. 5 from Dalgin et al., 2011
endocrine pancreas development decreased process quality, abnormal	AB + MO1-mnx1	Fig. 2 from Dalgin et al., 2011
pancreatic A cell differentiation increased occurrence, abnormal	AB + MO1-mnx1	Fig. 4 , Fig. 7 , Fig. S6 from Dalgin et al., 2011
posterior pancreatic bud has extra parts of type pancreatic A cell, abnormal	AB + MO1-mnx1	Fig. 4 , Fig. 7 , Fig. S6 from Dalgin et al., 2011
posterior pancreatic bud has fewer parts of type pancreatic B cell, abnormal	AB + MO1-mnx1	Fig. 2 , Fig. 4 , Fig. 7 from Dalgin et al., 2011
type B pancreatic cell differentiation decreased occurrence, abnormal	AB + MO1-mnx1	Fig. 4 , Fig. 7 from Dalgin et al., 2011

Phenotype of all Fish created by or utilizing MO1-mnx1

Phenotype	Fish	Conditions	Figures
posterior pancreatic bud has fewer parts of type pancreatic B cell, abnormal	AB + MO1-mnx1	standard conditions	Fig. 2 , Fig. 4 , Fig. 7 from Dalgin et al., 2011
pancreatic A cell differentiation increased occurrence, abnormal	AB + MO1-mnx1	chemical treatment: all-trans-retinoic acid	Fig. 7 from Dalgin et al., 2011
endocrine pancreas development increased process quality, abnormal	AB + MO1-mnx1	chemical treatment: all-trans-retinoic acid	Fig. 7 from Dalgin et al., 2011
posterior pancreatic bud has fewer parts of type pancreatic B cell, abnormal	AB + MO1-mnx1	chemical treatment: all-trans-retinoic acid	Fig. 7 from Dalgin et al., 2011
posterior pancreatic bud has extra parts of type pancreatic A cell, abnormal	AB + MO1-mnx1	chemical treatment: all-trans-retinoic acid	Fig. 7 from Dalgin et al., 2011
type B pancreatic cell differentiation decreased occurrence, abnormal	AB + MO1-mnx1	standard conditions	Fig. 4 , Fig. 7 from Dalgin et al., 2011
retinoic acid receptor signaling pathway increased occurrence, abnormal	AB + MO1-mnx1	chemical treatment: all-trans-retinoic acid	Fig. 7 from Dalgin et al., 2011
posterior pancreatic bud has extra parts of type pancreatic A cell, abnormal	AB + MO1-mnx1	standard conditions	Fig. 4 , Fig. 7 , Fig. S6 from Dalgin et al., 2011
type B pancreatic cell differentiation decreased occurrence, abnormal	AB + MO1-mnx1	chemical treatment: all-trans-retinoic acid	Fig. 7 from Dalgin et al., 2011
endocrine pancreas development decreased process quality, abnormal	AB + MO1-mnx1	standard conditions	Fig. 2 from Dalgin et al., 2011
pancreatic A cell differentiation increased occurrence, abnormal	AB + MO1-mnx1	standard conditions	Fig. 4 , Fig. 7 , Fig. S6 from Dalgin et al., 2011
endocrine pancreas has fewer parts of type pancreatic B cell, abnormal	nl1Tg + MO1-mnx1	standard conditions	Fig. 5 from Dalgin et al., 2011
endocrine pancreas has extra parts of type pancreatic A cell, abnormal	nl1Tg + MO1-mnx1	standard conditions	Fig. 5 from Dalgin et al., 2011

Citations