Morpholino

MO2-ppp1r12a

ID
ZDB-MRPHLNO-100525-6
Name
MO2-ppp1r12a
Previous Names
None
Target
Sequence
5' - ATTTTTTGTGACTTACTCAGCGATG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Splice-blocking MO.
Genome Resources
None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO2-ppp1r12a
Expressed Gene Anatomy Figures
epha4a Figure 3 with image from Cayuso et al., 2019
rfng Figure 3 with image,  Figure 4. with image from Cayuso et al., 2019
wwtr1 Figure 6 with image from Cayuso et al., 2019
Phenotype
Phenotype resulting from MO2-ppp1r12a
Phenotype Fish Figures
actin filament bundle distribution disrupted, abnormal AB + MO2-ppp1r12a Fig. 6 with image from Gutzman et al., 2015
midbrain hindbrain boundary basal side increased angle to brain epithelium, abnormal AB + MO2-ppp1r12a Fig. 3 with image from Gutzman et al., 2015
midbrain hindbrain boundary cell decreased length, abnormal AB + MO2-ppp1r12a Fig. 4 with image from Gutzman et al., 2015
midbrain hindbrain boundary cell increased area, abnormal AB + MO2-ppp1r12a Fig. 5 with image from Gutzman et al., 2015
midbrain hindbrain boundary cell increased width, abnormal AB + MO2-ppp1r12a Fig. 5 with image from Gutzman et al., 2015
midbrain hindbrain boundary constriction cell decreased length, abnormal WT + MO2-ppp1r12a Fig. 4 with image from Sahu et al., 2017
midbrain-hindbrain boundary morphogenesis disrupted, abnormal AB + MO2-ppp1r12a Fig. 3 with image from Gutzman et al., 2015
neuroepithelial cell actin filament decreased accumulation midbrain hindbrain boundary basal region, abnormal AB + MO2-ppp1r12a Fig. 6 with image from Gutzman et al., 2015
rhombomere 1 posterior margin rfng expression increased distribution, abnormal WT + MO2-ppp1r12a Figure 3 with image,  Figure 4. with image from Cayuso et al., 2019
rhombomere 2 posterior margin rfng expression increased distribution, abnormal WT + MO2-ppp1r12a Figure 3 with image,  Figure 4. with image from Cayuso et al., 2019
rhombomere 3 posterior margin rfng expression increased distribution, abnormal WT + MO2-ppp1r12a Figure 3 with image,  Figure 4. with image from Cayuso et al., 2019
rhombomere 3 posterior margin wwtr1 expression spatial pattern, abnormal WT + MO2-ppp1r12a Figure 6 with image from Cayuso et al., 2019
rhombomere 4 posterior margin rfng expression increased distribution, abnormal WT + MO2-ppp1r12a Figure 3 with image,  Figure 4. with image from Cayuso et al., 2019
rhombomere 4 posterior margin wwtr1 expression spatial pattern, abnormal WT + MO2-ppp1r12a Figure 6 with image from Cayuso et al., 2019
rhombomere 5 posterior margin rfng expression increased distribution, abnormal WT + MO2-ppp1r12a Figure 3 with image,  Figure 4. with image from Cayuso et al., 2019
rhombomere 6 posterior margin rfng expression increased distribution, abnormal WT + MO2-ppp1r12a Figure 3 with image,  Figure 4. with image from Cayuso et al., 2019
Phenotype of all Fish created by or utilizing MO2-ppp1r12a
Phenotype Fish Conditions Figures
midbrain hindbrain boundary cell decreased length, abnormal AB + MO2-ppp1r12a standard conditions Fig. 4 with image from Gutzman et al., 2015
midbrain hindbrain boundary cell increased width, abnormal AB + MO2-ppp1r12a standard conditions Fig. 5 with image from Gutzman et al., 2015
neuroepithelial cell actin filament decreased accumulation midbrain hindbrain boundary basal region, abnormal AB + MO2-ppp1r12a standard conditions Fig. 6 with image from Gutzman et al., 2015
midbrain hindbrain boundary cell increased area, abnormal AB + MO2-ppp1r12a standard conditions Fig. 5 with image from Gutzman et al., 2015
midbrain hindbrain boundary basal side increased angle to brain epithelium, abnormal AB + MO2-ppp1r12a standard conditions Fig. 3 with image from Gutzman et al., 2015
midbrain-hindbrain boundary morphogenesis disrupted, abnormal AB + MO2-ppp1r12a standard conditions Fig. 3 with image from Gutzman et al., 2015
actin filament bundle distribution disrupted, abnormal AB + MO2-ppp1r12a standard conditions Fig. 6 with image from Gutzman et al., 2015
rhombomere 5 posterior margin rfng expression increased distribution, abnormal WT + MO2-ppp1r12a standard conditions Figure 3 with image,  Figure 4. with image from Cayuso et al., 2019
rhombomere 3 posterior margin wwtr1 expression spatial pattern, abnormal WT + MO2-ppp1r12a standard conditions Figure 6 with image from Cayuso et al., 2019
rhombomere 6 posterior margin rfng expression increased distribution, abnormal WT + MO2-ppp1r12a standard conditions Figure 3 with image,  Figure 4. with image from Cayuso et al., 2019
midbrain hindbrain boundary constriction cell length, ameliorated WT + MO2-ppp1r12a chemical treatment by environment: 2-aminoethoxydiphenylborane Fig. 4 with image from Sahu et al., 2017
rhombomere 4 posterior margin rfng expression increased distribution, abnormal WT + MO2-ppp1r12a standard conditions Figure 3 with image,  Figure 4. with image from Cayuso et al., 2019
rhombomere 4 posterior margin wwtr1 expression spatial pattern, abnormal WT + MO2-ppp1r12a standard conditions Figure 6 with image from Cayuso et al., 2019
midbrain hindbrain boundary constriction cell decreased length, abnormal WT + MO2-ppp1r12a control Fig. 4 with image from Sahu et al., 2017
rhombomere 3 posterior margin rfng expression increased distribution, abnormal WT + MO2-ppp1r12a standard conditions Figure 3 with image,  Figure 4. with image from Cayuso et al., 2019
rhombomere 2 posterior margin rfng expression increased distribution, abnormal WT + MO2-ppp1r12a standard conditions Figure 3 with image,  Figure 4. with image from Cayuso et al., 2019
rhombomere 1 posterior margin rfng expression increased distribution, abnormal WT + MO2-ppp1r12a standard conditions Figure 3 with image,  Figure 4. with image from Cayuso et al., 2019
rhombomere 5 posterior margin rfng expression decreased distribution, abnormal epha4afci5/fci5 + MO2-ppp1r12a standard conditions Figure 4. with image from Cayuso et al., 2019
rhombomere 2 posterior margin rfng expression decreased distribution, abnormal epha4afci6/fci6 + MO2-ppp1r12a standard conditions Figure 4. with image from Cayuso et al., 2019
rhombomere 5 posterior margin rfng expression decreased distribution, abnormal epha4afci6/fci6 + MO2-ppp1r12a standard conditions Figure 4. with image from Cayuso et al., 2019
Citations
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