Morpholino

MO1-ndr2

ID

ZDB-MRPHLNO-060930-4

Name

MO1-ndr2

Previous Names

Cyclops-MO1 (1)

Target

ndr2 (1)

Sequence

5' - GCGACTCCGAGCGTGTGCATGATG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Contains a one base pair mismatch to minimize secondary structure (Karlen and Rebagliati (2001) Genesis 30: 126-128).

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-ndr2

Expressed Gene	Anatomy	Figures
zic1	presumptive forebrain	Fig. S1 from England et al., 2006

Phenotype

Phenotype resulting from MO1-ndr2

Phenotype	Fish	Figures
camera-type eye morphogenesis disrupted, abnormal	AB + MO1-ndr2	Fig. 4 from England et al., 2006
forebrain morphogenesis disrupted, abnormal	AB + MO1-ndr2	Fig. 3 from England et al., 2006

Phenotype of all Fish created by or utilizing MO1-ndr2

Phenotype	Fish	Conditions	Figures
camera-type eye morphogenesis disrupted, abnormal	AB + MO1-ndr2	standard conditions	Fig. 4 from England et al., 2006
forebrain morphogenesis disrupted, abnormal	AB + MO1-ndr2	standard conditions	Fig. 3 from England et al., 2006
endoderm formation decreased occurrence, abnormal	WT + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 3 from Pelliccia et al., 2017
notochord decreased thickness, abnormal	WT + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Fan et al., 2007
mesoderm formation decreased occurrence, abnormal	WT + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 3 from Pelliccia et al., 2017
shield decreased amount, abnormal	WT + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Fan et al., 2007
endoderm aplastic, abnormal	WT + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Fan et al., 2007
caudal fin morphology, abnormal	WT + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 3 from Pelliccia et al., 2017
formation of primary germ layer decreased process quality, abnormal	WT + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Kurup et al., 2024
notochord absent, abnormal	WT + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Kurup et al., 2024
shield aplastic, abnormal	WT + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Fan et al., 2007
eye fused with eye, abnormal	WT + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Fan et al., 2007
extension aplastic, abnormal	foxh1^pr1/pr1 + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Slagle et al., 2011
eye malformed, abnormal	foxh1^pr1/pr1 + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Slagle et al., 2011
whole organism anterior-posterior axis curved ventral, abnormal	foxh1^pr1/pr1 + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Slagle et al., 2011
post-vent region malformed, abnormal	foxh1^pr1/pr1 + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Slagle et al., 2011
head morphology, abnormal	foxh1^pr1/pr1 + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Slagle et al., 2011
head hypoplastic, abnormal	foxh1^pr1/pr1 + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Slagle et al., 2011
dorsal/ventral pattern formation disrupted, abnormal	foxh1^pr1/pr1 + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Slagle et al., 2011
endoderm formation decreased occurrence, abnormal	gdf3^pr05/pr05 + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 3 from Pelliccia et al., 2017
mesoderm formation decreased occurrence, abnormal	gdf3^pr05/pr05 + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 3 from Pelliccia et al., 2017
caudal fin morphology, exacerbated	gdf3^pr05/pr05 + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 3 from Pelliccia et al., 2017
notochord absent, exacerbated	myo1g^{nce18b/nce18b} + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Kurup et al., 2024
formation of primary germ layer decreased process quality, abnormal	myo1g^{nce18b/nce18b} + MO1-ndr2 + MO4-ndr1	standard conditions	Fig. 5 from Kurup et al., 2024

Citations