Morpholino

MO1-isl2a

ID

ZDB-MRPHLNO-060728-4

Name

MO1-isl2a

Previous Names

MO1-isl2 (1)

Target

isl2a (1)

Sequence

5' - GGATGCGGTAGAATATCCACCATAC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-isl2a

Expressed Gene	Anatomy	Figures
alcama	floor plate secondary motor neuron	Fig. 3 from Hutchinson et al., 2006
isl1a	whole organism	Fig. 7 from Moreno et al., 2018
isl2a	whole organism	Fig. 7 from Moreno et al., 2018
isl2b	whole organism	Fig. 7 from Moreno et al., 2018

Phenotype

Phenotype resulting from MO1-isl2a

Phenotype	Fish	Figures
CaP motoneuron axon branchiness, abnormal	AB + MO1-isl2a	Fig. 6 from Hutchinson et al., 2006
CaP motoneuron axon GFP expression decreased amount, abnormal	ml2Tg + MO1-isl2a	Fig. 4 from Moreno et al., 2018
CaP motoneuron axon morphology, abnormal	ml2Tg + MO1-isl2a	Fig. 4 from Moreno et al., 2018
CaP motoneuron axon truncated, abnormal	AB + MO1-isl2a	Fig. 4 from Moreno et al., 2018 Fig. 6 from Hutchinson et al., 2006
CaP motoneuron axon extension decreased process quality, abnormal	AB + MO1-isl2a	Fig. 6 from Hutchinson et al., 2006
CaP motoneuron axon guidance physical quality of a process, abnormal	AB + MO1-isl2a	Fig. 6 from Hutchinson et al., 2006
secondary motor neuron decreased amount, abnormal	WT + MO1-isl2a	Fig. 3 from Hutchinson et al., 2006
secondary motor neuron axon decreased amount, abnormal	rw0Tg + MO1-isl2a	Fig. 5 from Moreno et al., 2018 Fig. 3 from Hutchinson et al., 2006
secondary motor neuron cell body decreased amount, abnormal	rw0Tg + MO1-isl2a	Fig. 5 from Moreno et al., 2018
whole organism isl2a expression increased amount, abnormal	WT + MO1-isl2a	Fig. 7 from Moreno et al., 2018

Phenotype of all Fish created by or utilizing MO1-isl2a

Phenotype	Fish	Conditions	Figures
CaP motoneuron axon branchiness, abnormal	AB + MO1-isl2a	standard conditions	Fig. 6 from Hutchinson et al., 2006
CaP motoneuron axon extension decreased process quality, abnormal	AB + MO1-isl2a	standard conditions	Fig. 6 from Hutchinson et al., 2006
CaP motoneuron axon truncated, abnormal	AB + MO1-isl2a	standard conditions	Fig. 6 from Hutchinson et al., 2006
CaP motoneuron axon guidance physical quality of a process, abnormal	AB + MO1-isl2a	standard conditions	Fig. 6 from Hutchinson et al., 2006
secondary motor neuron axon decreased amount, abnormal	WT + MO1-isl2a	standard conditions	Fig. 3 from Hutchinson et al., 2006
secondary motor neuron decreased amount, abnormal	WT + MO1-isl2a	standard conditions	Fig. 3 from Hutchinson et al., 2006
whole organism isl2a expression increased amount, abnormal	WT + MO1-isl2a	standard conditions	Fig. 7 from Moreno et al., 2018
CaP motoneuron axon morphology, abnormal	ml2Tg + MO1-isl2a	standard conditions	Fig. 4 from Moreno et al., 2018
CaP motoneuron axon truncated, abnormal	ml2Tg + MO1-isl2a	standard conditions	Fig. 4 from Moreno et al., 2018
CaP motoneuron axon GFP expression decreased amount, abnormal	ml2Tg + MO1-isl2a	standard conditions	Fig. 4 from Moreno et al., 2018
secondary motor neuron cell body decreased amount, abnormal	rw0Tg + MO1-isl2a	standard conditions	Fig. 5 from Moreno et al., 2018
secondary motor neuron axon decreased amount, abnormal	rw0Tg + MO1-isl2a	standard conditions	Fig. 5 from Moreno et al., 2018
secondary motor neuron absent, abnormal	WT + MO1-isl2a + MO2-isl1a + MO3-isl1a	standard conditions	Fig. 3 from Hutchinson et al., 2006
presumptive sinus venosus cardiac muscle cell ab2-isl labeling absent, abnormal	isl1a^sa29/sa29; s883Tg + MO1-isl2a	standard conditions	Fig. 2 from Witzel et al., 2017
presumptive sinus venosus cardiac muscle cell ab2-isl labeling absent, abnormal	isl1a^sa29/sa29; s883Tg + MO1-isl2a + MO2-isl2b	standard conditions	Fig. 2 from Witzel et al., 2017

Citations