ZFIN Image: Xie et al., 2024, Fig. 6

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Figure Caption

Fig. 6 GTP compensation partially restored the hearing impairment caused by myo7aa deficiency. (A–D) YO-PRO-1 staining results of inner ear hair cells were observed in sibling (A), myo7aa−/− (B), GTP-compensated sibling (C), and myo7aa−/− (D) embryos at 5 dpf. (E,F) The relative expression of some genes in the cellular endocytic pathway (E) and G protein signaling pathway (F) is examined between WT, myo7aa−/−, and GTP-compensated myo7aa−/− embryos at 3 dpf is examined. (G,H) The movement distance (G) and reaction speed (H) of wild WT, myo7aa−/−, and GTP-compensated myo7aa−/− embryos are measured within 0.3 s after acoustic stimulation at 5 dpf are measured. n = 20; mean with SEM; with ANOVA, ****p < 0.0001, **p < 0.01, *p < 0.05, nsp > 0.05.

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.