ZFIN Image: Shi et al., 2023, Figure 4

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Figure 4

Chd7 knockout suppressed OPC migration. (a) Representative image of dorsally migrated olig2⁺ cells at 3, 4, 5, and 6 dpf between chd7^+/+ and chd7^−/− groups. Scale bar: 100 μm. (b) The number of dorsally migrated olig2⁺ cells at 3, 4, 5, and 6 dpf decreased in chd7^−/− group. Data shown as mean ± sem. 3 dpf, ** p = 0.0023; 4 dpf, **** p < 0.0001; 5 dpf, **** p < 0.0001; 6 dpf, p = 0.7349, ns: not significant, unpaired Student’s two-tailed t-test. (c) Representative image of total and dorsally migrated olig2⁺ cells at 4 dpf between chd7^+/+ and chd7^−/− group. Scale bar: 10 μm. (d) The number of total olig2⁺ cells at 4 dpf did not differ significantly between the two groups, ns: not significant. The number of dorsally migrated olig2⁺ cells at 4 dpf decreased in chd7^−/− group. ** p = 0.0075, unpaired Student’s two-tailed t-test.

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Acknowledgments

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